Protein Alignment Ser6 and Plat

DIOPT Version :10

• Sequence 1: NP_523426.1
• Gene: Ser6 / 33073
• FlyBaseID: FBgn0011834
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_032898.2
• Gene: Plat / 18791
• MGIID: 97610
• Length: 559
• Species: Mus musculus
• Alignment Length: 262
• Identity: 68/262 - (25%)
• Similarity: 113/262 - (43%)
• Gaps: 55/262 - (20%)

  Fly    31 RVVGG--EDAVKNQFPHQVSLRNAGSHS----CGGSILTRTYILTAAHC-VSNEDVNHVITPIAA 88
            |:.||  .|...:.:...:.::|..|..    |||.:::..::|:|||| :.....|| :..:..
Mouse   308 RIKGGLYTDITSHPWQAAIFVKNKRSPGERFLCGGVLISSCWVLSAAHCFLERFPPNH-LKVVLG 371

  Fly    89 ERFTIRAGSNDRFSGGVLVQVAEVIVHEEYGN--FLNDVALLRL---------ESPLILSASIQP 142
            ..:.:..|..::     ..::.:.|||||:.:  :.||:|||:|         ||..:.:|.:..
Mouse   372 RTYRVVPGEEEQ-----TFEIEKYIVHEEFDDDTYDNDIALLQLRSQSKQCAQESSSVGTACLPD 431

  Fly   143 IDLPTVDTPADVDVVISGWGRIKHQGDLPRY---LQYNTLKSITRQQCEELIDFG---FEGELCL 201
               |.:..|...:..:||:|  ||:...|.:   |:...::.....:|.....|.   ....||.
Mouse   432 ---PNLQLPDWTECELSGYG--KHEASSPFFSDRLKEAHVRLYPSSRCTSQHLFNKTVTNNMLCA 491

  Fly   202 ----------LHQVDNGACNGDSGGPAV--YNNQ--LVGVAGFVVDGCG-STYPDGYARVFYFKD 251
                      ||.    ||.||||||.|  .|.|  |.|:..:.: ||| ...|..|.:|..:.|
Mouse   492 GDTRSGGNQDLHD----ACQGDSGGPLVCMINKQMTLTGIISWGL-GCGQKDVPGVYTKVTNYLD 551

  Fly   252 WI 253
            ||
Mouse   552 WI 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	67/261 (26%)
Plat	NP_032898.2	FN1	38..80	CDD:214494
		Important for binding to annexin A2. /evidence=ECO:0000250	39..49
		EGF	83..115	CDD:394967
		Kringle	124..205	CDD:395005
		KR	210..295	CDD:238056
		Tryp_SPc	311..556	CDD:238113	67/259 (26%)