Protein Alignment Ser6 and KLK8

DIOPT Version :10

• Sequence 1: NP_523426.1
• Gene: Ser6 / 33073
• FlyBaseID: FBgn0011834
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 66/250 - (26%)
• Similarity: 107/250 - (42%)
• Gaps: 27/250 - (10%)

  Fly    20 PVQSAPGKLNG---RVVGGEDAVKNQFPHQVSLRNAGSHSCGGSILTRTYILTAAHCVSNEDVNH 81
            |:..|.|....   :|:||.:...:..|.|.:|.......|||.::...::||||||
Human    63 PLPPAAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC-------- 119

  Fly    82 VITPIAAERFTIRAGSN---DRFSGGVLVQVAEVIVHEEYG-----NFLNDVALLRLESPLILSA 138
                 ...::|:|.|.:   ::......:.|.:.|.|..|.     :..:|:.||:|.....|.:
Human   120 -----KKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGS 179

  Fly   139 SIQPIDLPTVDTPADVDVVISGWGRI-KHQGDLPRYLQYNTLKSITRQQCEELIDFGF-EGELCL 201
            .::||.|....|.......:||||.: ..:.:.|..|....:|...:::||:...... :|.:|.
Human   180 KVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCA 244

  Fly   202 LHQVDNGACNGDSGGPAVYNNQLVGVAGFVVDGCG-STYPDGYARVFYFKDWIKK 255
            ........|.||||||.|.:..|.|:..:..|.|| |..|..|..:..:.|||||
Human   245 GSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	62/234 (26%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	59/232 (25%)