| Sequence 1: | NP_608417.2 | Gene: | Npc1b / 33072 | FlyBaseID: | FBgn0261675 | Length: | 1254 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001120162.1 | Gene: | scap / 100145201 | XenbaseID: | XB-GENE-996521 | Length: | 1319 | Species: | Xenopus tropicalis |
| Alignment Length: | 671 | Identity: | 138/671 - (20%) |
|---|---|---|---|
| Similarity: | 253/671 - (37%) | Gaps: | 177/671 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 309 FFYHGFRIWGTFCAKHP---VIVLALCSWA---------IAGLSFGIRYMTITTD--PVELWAGE 359
Fly 360 ESQTRIEKDYFDQHFG-PFYRTNQMFVKAVNQTYFTHETSNGVLNFGPAFEYNFLKEVFELQDSI 423
Fly 424 MKLGM---ADNEGLDKICYAPV-LMAGETPTVDR-----CAIQSVYGYFQHDMDRFE------NS 473
Fly 474 YVDSNNYTINYLNQLEDCLRVPMMEDCFGTFGGP-IEPGIAVGGMPKVAVGEDPDYMLATGLVLT 537
Fly 538 FLGRNYNDESKLEPNMKWEKLFVDFLRDYKSDRLDIAYMAERSIQDA--IV------ELSEGEVS 594
Fly 595 TVVISYVVMFVYVAIALGHIRSCRGFLRESRIMLAIGGIVIVLASVVCSLGFWGYLDVTTTMLAI 659
Fly 660 EVIPFLVLAVGVDNIFIM----VHTYQRLDHSKFKTTHEAIGEAIGQVGPSILQTAGSEMACFAI 720
Fly 721 GCISDMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDEKRY----LDGRLDMLCCV---KSGGK 778
Fly 779 KINDEDGDGVDRPKEVGLLETLFKNFYSPFLLSKPVKVSVLLIFTVITCLSLMVTPSIEKGLDQE 843
Fly 844 MSMPKNSHVVKYF--RYMVDLLAMGAPVYWVLKPG-LNYSEPLQQNLICGGVECNNNSLSVQLYT 905
Fly 906 Q-----AQYPEITSLARPASS 921 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Npc1b | NP_608417.2 | 2A060601 | 24..1220 | CDD:273337 | 138/671 (21%) |
| NPC1_N | 24..270 | CDD:293023 | |||
| nitrilase | <265..>331 | CDD:299711 | 7/24 (29%) | ||
| Sterol-sensing | 623..775 | CDD:289145 | 41/162 (25%) | ||
| scap | NP_001120162.1 | 2A060601 | <11..>446 | CDD:273337 | 107/496 (22%) |
| Sterol-sensing | 306..452 | CDD:372063 | 40/151 (26%) | ||
| WD40 | 795..826 | CDD:197651 | |||
| WD40 | <993..1195 | CDD:225201 | |||
| WD40 repeat | 1050..1086 | CDD:293791 | |||
| WD40 | 1118..>1275 | CDD:392136 | |||
| WD40 repeat | 1123..1157 | CDD:293791 | |||
| WD40 repeat | 1162..1197 | CDD:293791 | |||
| WD40 repeat | 1204..1237 | CDD:293791 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||