DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15450 and LPGAT1

DIOPT Version :9

Sequence 1:	NP_608409.1	Gene:	CG15450 / 33064	FlyBaseID:	FBgn0031132	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001362773.1	Gene:	LPGAT1 / 9926	HGNCID:	28985	Length:	403	Species:	Homo sapiens

Alignment Length:	269	Identity:	55/269 - (20%)
Similarity:	84/269 - (31%)	Gaps:	110/269 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 VTQRFVAPPSPAGEWNLLTRNLRQRNRYLSWRLRTV---WLLGWVVRYGLLLPFRTIGCWLCLFM 162
            |....||.||... :.::.:.||..:....|.:..:   ||||.|..:|          |...:.
Human    59 VVNNLVAIPSYIC-YVIILQPLRVLDSKRFWYIEGIMYKWLLGMVASWG----------WYAGYT 112

  Fly   163 -------ISGVS-----MLLGH--IPDWCFKKKLVELVLRQCFRITAACLPMIRRFHNTEYRPTK 213
                   |..||     ||:.|  ..|.|        .|..|.:                   .|
Human   113 VMEWGEDIKAVSKDEAVMLVNHQATGDVC--------TLMMCLQ-------------------DK 150

  Fly   214 GICVCNHTSPLDVLVLMCDANYSLTGQVHTGILGVLQRALSRVSHHMWFDRKELADREALGLVLR 278
            |:.|..       ::.:.|..:..|   :.||:.::        |..:|.|:..:.|:...|:|:
Human   151 GLVVAQ-------MMWLMDHIFKYT---NFGIVSLV--------HGDFFIRQGRSYRDQQLLLLK 197

  Fly   279 LHCS----MKDRPPVLLFPEG---------------------------------TCINNTAVMQF 306
            .|..    .:||..::|||||                                 ..|.|..|.|.
Human   198 KHLENNYRSRDRKWIVLFPEGGFLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQ 262

  Fly   307 KKGSFAVSD 315
            |.||.|..|
Human   263 KNGSPAGGD 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15450	NP_608409.1	LPLAT_LPCAT1-like	191..399	CDD:153253	30/162 (19%)
LPGAT1	NP_001362773.1	LPLAT_LCLAT1-like	102..318	CDD:153252	43/225 (19%)
LPGAT1	NP_001362773.1	Acyltransf_C	307..376	CDD:374349
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900