DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15450 and YDR018C

DIOPT Version :9

Sequence 1:	NP_608409.1	Gene:	CG15450 / 33064	FlyBaseID:	FBgn0031132	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_010301.1	Gene:	YDR018C / 851581	SGDID:	S000002425	Length:	396	Species:	Saccharomyces cerevisiae

Alignment Length:	219	Identity:	40/219 - (18%)
Similarity:	72/219 - (32%)	Gaps:	80/219 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 RQCFRITAACLPMIRRFHNTEYRPTKGICVCNHTSPLDVLVLMCDANYS-LTGQVHTGILGVLQR 251
            :.|||.                 ..:.|.:.||....|.:.|...:..| |.|.|:.    :|::
Yeast   102 KPCFRF-----------------KDRAIIIANHQMYADWIYLWWLSFVSNLGGNVYI----ILKK 145

  Fly   252 ALS---------RVSHHMWFDRKELADREAL-GLVLRLHCSMKDRPP------------------ 288
            ||.         |....::..|....|.:|| ..::.:..:.:.:.|
Yeast   146 ALQYIPLLGFGMRNFKFIFLSRNWQKDEKALTNSLVSMDLNARCKGPLTNYKSCYSKTNESIAAY 210

  Fly   289 -VLLFPEGTCIN---------------------NTAVMQFKKG-SFAVS------DVVHPVAIRY 324
             :::|||||.::                     ...::...|| .|||.      |.::.|.|.|
Yeast   211 NLIMFPEGTNLSLKTREKSEAFCQRAHLDHVQLRHLLLPHSKGLKFAVEKLAPSLDAIYDVTIGY 275

  Fly   325 DRRFGEAYWDSTRYSMLRYMLMVV 348
            .......| ..|::::.:..||.|
Yeast   276 SPALRTEY-VGTKFTLKKIFLMGV 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15450	NP_608409.1	LPLAT_LPCAT1-like	191..399	CDD:153253	39/216 (18%)
YDR018C	NP_010301.1	LPLAT_LCLAT1-like	102..308	CDD:153252	40/219 (18%)
YDR018C	NP_010301.1	Acyltransf_C	300..>347	CDD:406475
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900