DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15450 and gpat4

DIOPT Version :9

Sequence 1:	NP_608409.1	Gene:	CG15450 / 33064	FlyBaseID:	FBgn0031132	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001035339.2	Gene:	gpat4 / 678522	ZFINID:	ZDB-GENE-060421-5102	Length:	451	Species:	Danio rerio

Alignment Length:	413	Identity:	158/413 - (38%)
Similarity:	239/413 - (57%)	Gaps:	30/413 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLIQLVFLGILLWASFFWLQCRYLDVLELLFAWIGNQLAETRRRR-AREERCRLGKKWAVGNKGD 64
            :|:..:.:..:|..| |.::..|:..|..||.|     |..|..| |||:...|.|.::.|
Zfish    26 LLLVFIIVPAILGVS-FGIRRLYMMSLIKLFEW-----ATLRMERGAREKNQHLYKPYSNG---- 80

  Fly    65 GMEKLLSPPIKNRLNIR------------VEQCCDFITAGLGLVLEDDVTQRFVAPPSPAGEWNL 117
               .:...|......|:            :.....|...|:..:::|:||:||.|  .....|||
Zfish    81 ---IIAKEPASLEQEIQEMRRGGAEPEFDMSDIFHFCRRGVESIVDDEVTKRFTA--EELESWNL 140

  Fly   118 LTRNLRQRNRYLSWRLRTVWLLGWVVRYGLLLPFRTIGCWLCLFMISGVSMLLGHIPDWCFKKKL 182
            |||: .....::|.||..:|.:|.::|||.|||.|....:..:.::..::.::|..|:...|..|
Zfish   141 LTRS-NYNFHHISTRLTALWGVGVLIRYGFLLPLRVTLAFTGVGLLVVLTSIVGLFPNGRMKNYL 204

  Fly   183 VELVLRQCFRITAACLPMIRRFHNTEYRPTK-GICVCNHTSPLDVLVLMCDANYSLTGQVHTGIL 246
            .:.|...|:||....|..|..:|::|.:|.. ||||.|||||:||::|..|..|::.||||.|::
Zfish   205 SDKVHLMCYRICVRALTAIITYHDSENKPKNGGICVANHTSPIDVIILASDGCYAMVGQVHGGLM 269

  Fly   247 GVLQRALSRVSHHMWFDRKELADREALGLVLRLHCSMKDRPPVLLFPEGTCINNTAVMQFKKGSF 311
            ||:|||:.:...|:||:|.|:.||..:...|..|.:.:.:.|:|:||||||||||:||.||||||
Zfish   270 GVIQRAMVKACPHIWFERSEVKDRHLVAKRLSDHVADESKLPILIFPEGTCINNTSVMMFKKGSF 334

  Fly   312 AVSDVVHPVAIRYDRRFGEAYWDSTRYSMLRYMLMVVSSWCICCDVWYMPALSRCNDESPVEFSN 376
            .:...|:||||:||.|||:|:|:|:::.|:.|:|.::|||.|.|.|||:|.:||...|..|:|:|
Zfish   335 EIGCTVYPVAIKYDPRFGDAFWNSSKFGMVNYLLHMMSSWAIVCSVWYLPPMSRMEGEDAVQFAN 399

  Fly   377 RVKAAIAAQANIDDLPWDGNLKR 399
            |||||||.:..:.||.|||.|||
Zfish   400 RVKAAIARKGGLADLLWDGGLKR 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15450	NP_608409.1	LPLAT_LPCAT1-like	191..399	CDD:153253	104/208 (50%)
gpat4	NP_001035339.2	LPLAT_LPCAT1-like	213..422	CDD:153253	104/208 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	294	1.000	Inparanoid score	I2748
OMA	1	1.010	-	-		QHG55588
OrthoDB	1	1.010	-	-		D232807at33208
OrthoFinder	1	1.000	-	-		FOG0001324
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23063
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1369
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.940