DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15450 and AGPAT3

DIOPT Version :9

Sequence 1:	NP_608409.1	Gene:	CG15450 / 33064	FlyBaseID:	FBgn0031132	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_011527964.1	Gene:	AGPAT3 / 56894	HGNCID:	326	Length:	463	Species:	Homo sapiens

Alignment Length:	295	Identity:	62/295 - (21%)
Similarity:	92/295 - (31%)	Gaps:	107/295 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 CRLG------KKWAVGNKG-DGMEKLLSPPIKNRLNIRVEQCCDFITAGLGLVLEDDVTQRFVAP 108
            |.||      :|...|..| |.|...:..|::                      :|...||....
Human    39 CALGAVPGPSQKHRAGPAGPDAMGFCVCEPLE----------------------KDGCPQRGAVH 81

  Fly   109 PSPAGEWNLLTRNLRQRNRYLSWRLRTVWLLGWV-VRYGLLLPF----------------RTIGC 156
            |..:....||.        :|..:.....|:|:| |..||::.|                |.:.|
Human    82 PLLSSAMGLLA--------FLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNC 138

  Fly   157 WLCLFMISGVSMLLGHIPDW--CFKKKLVELVLRQCFRITAACLPMIRRFHNTEYRPTKGICVCN 219
            .|...:.|.:.|||    :|  |          .:|...|...  .:.||....     .:.:.|
Human   139 RLAYSLWSQLVMLL----EWWSC----------TECTLFTDQA--TVERFGKEH-----AVIILN 182

  Fly   220 HTSPLDVLV--LMCDANYSLTGQVHTGILG----VLQRALSRVSHHMW---------FDRKELAD 269
            |...:|.|.  .||:         ..|:||    :.::.|..|....|         ..||...|
Human   183 HNFEIDFLCGWTMCE---------RFGVLGSSKVLAKKELLYVPLIGWTWYFLEIVFCKRKWEED 238

  Fly   270 REALGLVLRLHCSMKDRPP---VLLFPEGTCINNT 301
            |:.:...||   .:.|.|.   .||:.|||....|
Human   239 RDTVVEGLR---RLSDYPEYMWFLLYCEGTRFTET 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15450	NP_608409.1	LPLAT_LPCAT1-like	191..399	CDD:153253	29/129 (22%)
AGPAT3	XP_011527964.1	PLN02380	104..412	CDD:178006	45/200 (23%)
		LPLAT_LCLAT1-like	149..343	CDD:153252	35/155 (23%)
		Acyltransf_C	330..401	CDD:292694
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900