DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15450 and Gpat3

DIOPT Version :9

Sequence 1:	NP_608409.1	Gene:	CG15450 / 33064	FlyBaseID:	FBgn0031132	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001020841.1	Gene:	Gpat3 / 305166	RGDID:	1565703	Length:	457	Species:	Rattus norvegicus

Alignment Length:	410	Identity:	167/410 - (40%)
Similarity:	245/410 - (59%)	Gaps:	20/410 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LVFLG-ILLWASFFWLQCR----YLDVLELLFAWIGNQLAETRRRRAREERCRLGKKWAVG---N 61
            |..:| ::|..|.|.|...    |:.:|.....|     |..|..:...:...|....::|   .
  Rat    15 LTLVGSLILLPSAFGLSLGISEIYMKILVKTLEW-----ATLRIEKGAPKESVLKSPASMGIIQR 74

  Fly    62 KGDGMEKLLSPPIKNRLNIRVEQCCDFITAGLGLVLEDDVTQRFVAPPSPAGEWNLLTRNLRQRN 126
            ....|||.|| .::.| :..:.....|...||..::||:|||||.:  .....||||||. ....
  Rat    75 DESPMEKGLS-GLRGR-DFELSDVFYFSKKGLEAIVEDEVTQRFSS--EELVSWNLLTRT-NVNF 134

  Fly   127 RYLSWRLRTVWLLGWVVRYGLLLPFRTIGCWLCLFMISGVSMLLGHIPDWCFKKKLVELVLRQCF 191
            .|:|.:|..||:||.:|||..|||.|....::.:.::...:.|:|.:||...|..|.|||...|.
  Rat   135 HYISPKLTIVWVLGVLVRYCFLLPLRVTLAFIGISLLIIGTTLVGQLPDSSLKNWLSELVHLTCC 199

  Fly   192 RITAACLPMIRRFHNTEYRPTK-GICVCNHTSPLDVLVLMCDANYSLTGQVHTGILGVLQRALSR 255
            ||....|.....:||.:|||.| ||||.|||||:|||:|..|..|::.||||.|::|::|||:.:
  Rat   200 RICVRSLSGTIHYHNKQYRPQKGGICVANHTSPIDVLILATDGCYAMVGQVHGGLMGIIQRAMVK 264

  Fly   256 VSHHMWFDRKELADREALGLVLRLHCSMKDRPPVLLFPEGTCINNTAVMQFKKGSFAVSDVVHPV 320
            ...|:||:|.|:.||..:...|:.|.:.|.:.|:|:||||||||||:||.||||||.:...::||
  Rat   265 ACPHVWFERSEIKDRHLVTKRLKEHIADKKKLPILIFPEGTCINNTSVMMFKKGSFEIGGTIYPV 329

  Fly   321 AIRYDRRFGEAYWDSTRYSMLRYMLMVVSSWCICCDVWYMPALSRCNDESPVEFSNRVKAAIAAQ 385
            ||:|:.:||:|:|:|::|:::.|:|.:::||.|.|||||||.::|...|..|:|:||||:|||.|
  Rat   330 AIKYNPQFGDAFWNSSKYNLVSYLLRIMTSWAIVCDVWYMPPMTREEGEDAVQFANRVKSAIAVQ 394

  Fly   386 ANIDDLPWDGNLKRWSPVRD 405
            ..:.:|||||.||| :.|:|
  Rat   395 GGLTELPWDGGLKR-AKVKD 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15450	NP_608409.1	LPLAT_LPCAT1-like	191..399	CDD:153253	104/208 (50%)
Gpat3	NP_001020841.1	LPLAT_LPCAT1-like	199..408	CDD:153253	104/208 (50%)
		HXXXXD motif. /evidence=ECO:0000250\|UniProtKB:Q9D517	229..234		4/4 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	429..457
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353912
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	301	1.000	Inparanoid score	I2598
OMA	1	1.010	-	-		QHG55588
OrthoDB	1	1.010	-	-		D232807at33208
OrthoFinder	1	1.000	-	-		FOG0001324
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23063
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1369
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.870