Protein Alignment CG15450 and GPAT4

DIOPT Version :10

• Sequence 1: NP_608409.1
• Gene: CG15450 / 33064
• FlyBaseID: FBgn0031132
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_848934.1
• Gene: GPAT4 / 137964
• HGNCID: 20880
• Length: 456
• Species: Homo sapiens
• Alignment Length: 427
• Identity: 165/427 - (38%)
• Similarity: 249/427 - (58%)
• Gaps: 37/427 - (8%)

  Fly     1 MLIQLVFLGILLWASF---FWLQCRYLDVLELLFAWIGNQLAETRRRR-AREERCRLGKKWA--- 58
            :|..|:.:.|::.|.|   |.::..|:..|..:|||     |..|..| |:|:..:|.|.:.
Human    21 VLFTLLLVFIIVPAIFGVSFGIRKLYMKSLLKIFAW-----ATLRMERGAKEKNHQLYKPYTNGI 80

  Fly    59 VGNKGDGMEKLL--------SPPIKNRLNIRVEQCCDFITAGLGLVLEDDVTQRFVAPPSPAGEW 115
            :......:|:.:        |..:.|.....:.....|...|:..:::|:||:||.|  .....|
Human    81 IAKDPTSLEEEIKEIRRSGSSKALDNTPEFELSDIFYFCRKGMETIMDDEVTKRFSA--EELESW 143

  Fly   116 NLLTRNLRQRNRYLSWRLRTVWLLGWVVRYGLLLPFRTIGCWLCLFMISGVSML------LGHIP 174
            |||:|. ....:|:|.||..:|.||.::||..|||.|      .....:|:|:|      :|::|
Human   144 NLLSRT-NYNFQYISLRLTVLWGLGVLIRYCFLLPLR------IALAFTGISLLVVGTTVVGYLP 201

  Fly   175 DWCFKKKLVELVLRQCFRITAACLPMIRRFHNTEYRPTK-GICVCNHTSPLDVLVLMCDANYSLT 238
            :..||:.:.:.|...|:||....|..|..:|:.|.||.. ||||.|||||:||::|..|..|::.
Human   202 NGRFKEFMSKHVHLMCYRICVRALTAIITYHDRENRPRNGGICVANHTSPIDVIILASDGYYAMV 266

  Fly   239 GQVHTGILGVLQRALSRVSHHMWFDRKELADREALGLVLRLHCSMKDRPPVLLFPEGTCINNTAV 303
            ||||.|::||:|||:.:...|:||:|.|:.||..:...|..|...|.:.|:|:||||||||||:|
Human   267 GQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHLVAKRLTEHVQDKSKLPILIFPEGTCINNTSV 331

  Fly   304 MQFKKGSFAVSDVVHPVAIRYDRRFGEAYWDSTRYSMLRYMLMVVSSWCICCDVWYMPALSRCND 368
            |.||||||.:...|:||||:||.:||:|:|:|::|.|:.|:|.:::||.|.|.|||:|.::|..|
Human   332 MMFKKGSFEIGATVYPVAIKYDPQFGDAFWNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTREAD 396

  Fly   369 ESPVEFSNRVKAAIAAQANIDDLPWDGNLKRWSPVRD 405
            |..|:|:||||:|||.|..:.||.|||.||| ..|:|
Human   397 EDAVQFANRVKSAIARQGGLVDLLWDGGLKR-EKVKD 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15450	NP_608409.1	LPLAT_LPCAT1-like	191..399	CDD:153253	105/208 (50%)
GPAT4	NP_848934.1	LPLAT_LPCAT1-like	218..427	CDD:153253	105/208 (50%)
		HXXXXD motif. /evidence=ECO:0000250|UniProtKB:Q9D517	248..253		4/4 (100%)