DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15450 and Aup1

DIOPT Version :9

Sequence 1:	NP_608409.1	Gene:	CG15450 / 33064	FlyBaseID:	FBgn0031132	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_031543.3	Gene:	Aup1 / 11993	MGIID:	107789	Length:	410	Species:	Mus musculus

Alignment Length:	257	Identity:	62/257 - (24%)
Similarity:	106/257 - (41%)	Gaps:	52/257 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 LLPFRTIG-CWLCLFMISGVSMLLGH--IPDWCFKKKLVELVLRQCFRITAACLPMIRRFHNTEY 209
            ||.:..:| |.|.|.:..|:.:.|..  :||...::.:|        |...|.|.::.|..::..
Mouse    28 LLLYAPVGLCLLVLRLFLGLHVFLVSCALPDSVLRRFVV--------RTMCAVLGLVARQEDSGL 84

  Fly   210 RPTK-GICVCNHTSPLDVLVLMCDANYSLTGQVHTGILGVLQRALSRVSHHMW------FDRK-E 266
            |..: .:.:.||.:|.|..::      :|.....|.:|.      |..|...|      .||: |
Mouse    85 RDHRVRVLISNHVTPFDHNIV------NLLTTCSTPLLN------SPPSFVCWSRGFMEMDRRVE 137

  Fly   267 LADREALGLVLRLHCSMKDRP--PVLLFPEGTCIN-NTAVMQFKKGSFAVSDVVHPVAIRYDR-- 326
            |.:.      |:..|:....|  |:|||||....| ...:::|....|::.|||.|:.::..|
Mouse   138 LVES------LKKFCASTRLPPTPLLLFPEEEATNGREGLLRFSSWPFSIQDVVQPLTLQVQRPL 196

  Fly   327 ---RFGEAYWDSTRYSMLRYMLMVVSSWCICCDVWYMPALSRCNDESPVEFSNRVKAAIAAQ 385
               ...:|.|    .|.|.:.|.|  .:.:....|..|...:..:||. ||:.||:..:|.:
Mouse   197 VSVTVSDASW----VSELLWSLFV--PFTVYQVRWLHPIRRQLGEESE-EFALRVQQLVAKE 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15450	NP_608409.1	LPLAT_LPCAT1-like	191..399	CDD:153253	51/211 (24%)
Aup1	NP_031543.3	LPLAT	66..264	CDD:418432	52/219 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	258..295
		CUE_AUP1	296..340	CDD:270603
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	344..369
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810