DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15450 and Gpat4

DIOPT Version :9

Sequence 1:	NP_608409.1	Gene:	CG15450 / 33064	FlyBaseID:	FBgn0031132	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_011240406.1	Gene:	Gpat4 / 102247	MGIID:	2142716	Length:	462	Species:	Mus musculus

Alignment Length:	437	Identity:	169/437 - (38%)
Similarity:	248/437 - (56%)	Gaps:	51/437 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLIQLVFLGILLWASF---FWLQCRYLDVLELLFAWIGNQLAETRRRR-AREERCRLGKKWAVG- 60
            :|..|:.:.|::.|.|   |.::..|:..|..:|||     |..|..| |:|...:|.|.:..|
Mouse    21 VLFTLLLVFIIVPAIFGVSFGIRKLYMKTLLKIFAW-----ATLRMERGAKERNHQLYKPYTNGI 80

  Fly    61 --------------NKGDGMEKLLSPPIKNRLNIRVEQCCDFITAGLGLVLEDDVTQRFVAPPSP 111
                          .:..|..|.|....:..|:    ....|...|:..:::|:||:||.|  ..
Mouse    81 IAKDPTSLEEEIKEIRRSGSSKALDKTPEFELS----DIFYFCRKGMETIMDDEVTKRFSA--EE 139

  Fly   112 AGEWNLLTRNLRQRNRYLSWRLRTVWLLGWVVRYGLLLPFRT------IGCWLCLFMISGVSMLL 170
            ...||||:|. ....:|:|.||..:|.||.::||..|||.|.      ||     .::.|.:| :
Mouse   140 LESWNLLSRT-NYNFQYISLRLTILWGLGVLIRYCFLLPLRIALAFTGIG-----LLVVGTTM-V 197

  Fly   171 GHIPDWCFKKKLVELVLRQCFRITAACLPMIRRFHNTEYRPTK-GICVCNHTSPLDVLVLMCDAN 234
            |::|:..||:.|.:.|...|:||....|..|..:||.:.||.. ||||.|||||:||::|..|..
Mouse   198 GYLPNGRFKEFLSKHVHLMCYRICVRALTAIITYHNRKNRPRNGGICVANHTSPIDVIILASDGY 262

  Fly   235 YSLTGQVHTGILGVLQRALSRVSHHMWFDRKELADREALGLVLRLHCSMKDRPPVLLFPEGTCIN 299
            |::.||||.|::||:|||:.:...|:||:|.|:.||..:...|..|...|.:.|:|:||||||||
Mouse   263 YAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHLVAKRLTEHVQDKSKLPILIFPEGTCIN 327

  Fly   300 NTAVMQFKKGSFAVSDVVHPVAIR------YDRRFGEAYWDSTRYSMLRYMLMVVSSWCICCDVW 358
            ||:||.||||||.:...|:||||:      ||.:||:|:|:|::|.|:.|:|.:::||.|.|.||
Mouse   328 NTSVMMFKKGSFEIGATVYPVAIKPPLLVQYDPQFGDAFWNSSKYGMVTYLLRMMTSWAIVCSVW 392

  Fly   359 YMPALSRCNDESPVEFSNRVKAAIAAQANIDDLPWDGNLKRWSPVRD 405
            |:|.::|..||..|:|:||||:|||.|..:.||.|||.||| ..|:|
Mouse   393 YLPPMTREKDEDAVQFANRVKSAIARQGGLVDLLWDGGLKR-EKVKD 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15450	NP_608409.1	LPLAT_LPCAT1-like	191..399	CDD:153253	105/214 (49%)
Gpat4	XP_011240406.1	LPLAT_LPCAT1-like	218..433	CDD:153253	105/214 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	303	1.000	Inparanoid score	I2642
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55588
OrthoDB	1	1.010	-	-		D232807at33208
OrthoFinder	1	1.000	-	-		FOG0001324
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23063
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1369
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.940