DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15450 and Lpcat2

DIOPT Version :9

Sequence 1:	NP_608409.1	Gene:	CG15450 / 33064	FlyBaseID:	FBgn0031132	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001258273.1	Gene:	Lpcat2 / 100359680	RGDID:	2325051	Length:	544	Species:	Rattus norvegicus

Alignment Length:	356	Identity:	83/356 - (23%)
Similarity:	135/356 - (37%)	Gaps:	87/356 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 FVAPPSPAGEWNLLTRNLRQRNRYLSWRLRTVWLLGWVVRYGLLLPFRTIGCWLCLFMISGVSML 169
            |..||.|        ....|:.|..:.|...:.|||.:     |||.|.        ::.|:.:|
  Rat    35 FFPPPVP--------NPFVQQTRISAARRLQMILLGII-----LLPVRA--------LLVGLVLL 78

  Fly   170 LGHIPDW--------CFKKKLVELVLRQCFRITAACLPMIRR--FHNTEYRPT-KG--------- 214
            |.    |        |..|||...:.....:||...|..:.|  |.:..:|.| ||
  Rat    79 LA----WPFAVISTVCCPKKLTHPISDWRRKITQPALKFLGRAMFFSMGFRVTVKGKVASPLEAP 139

  Fly   215 -ICVCNHTSPLDVLVLMCDANYSLTGQ---VHTGILGVLQRAL-----SRVSHHMWFDRKELADR 270
             ..|..|::..|.:..:.....||..:   ..|.::|.|.|||     |||...        :.:
  Rat   140 IFVVAPHSTFFDGIACVVAGLPSLVSRNENAQTPLVGRLLRALQPVLVSRVDPD--------SRK 196

  Fly   271 EALGLVLRLHCSMKDRPPVLLFPEGTCINNTAVMQFKKGSFAVSDVVHPVAIRYDRRFGEAYWDS 335
            ..:..:.:...|..:.|.:|:||||||.|.:.::.||.|:|.....|.||.:||..:.....|..
  Rat   197 NTINEIKKRAMSGGEWPQILVFPEGTCTNRSCLITFKPGAFIPGVPVQPVLLRYPNKLDTVTWTW 261

  Fly   336 TRYSMLRYMLMVVSSWCICCDVWYMPALSRCNDE--SPVEFSNRVKAAIAAQANI-------DD- 390
            ..|:.::..::.........:|.:||..:...:|  .||.|::||:..:|....|       :|
  Rat   262 QGYTFIQLCVLTFCQLFTKVEVEFMPVQAPSEEERNDPVLFASRVRNLMAEALEIPVTDHTYEDC 326

  Fly   391 ----------LPWDGNLKRWSPVR-----DW 406
                      ||.:..|..::.:.     ||
  Rat   327 RLMISAGQLTLPMEAGLVEFTKISRKLKLDW 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15450	NP_608409.1	LPLAT_LPCAT1-like	191..399	CDD:153253	59/248 (24%)
Lpcat2	NP_001258273.1	PlsC	103..>254	CDD:223282	42/158 (27%)
		LPLAT_LPCAT1-like	116..327	CDD:153253	53/218 (24%)
		HXXXXD motif. /evidence=ECO:0000250\|UniProtKB:Q3TFD2	146..151		1/4 (25%)
		EGTC motif	220..223		2/2 (100%)
		EFh	396..458	CDD:238008
		EF-hand_7	396..457	CDD:290234
		EF-hand_7	433..489	CDD:290234
		EFh	433..486	CDD:238008
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	520..544
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810