Protein Alignment shakB and inx-20

DIOPT Version :9

• Sequence 1: NP_608410.2
• Gene: shakB / 33062
• FlyBaseID: FBgn0085387
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_001251235.1
• Gene: inx-20 / 188818
• WormBaseID: WBGene00002142
• Length: 483
• Species: Caenorhabditis elegans
• Alignment Length: 437
• Identity: 98/437 - (22%)
• Similarity: 182/437 - (41%)
• Gaps: 82/437 - (18%)

  Fly   132 ADTVKQYISRAQRTTKKGSQEQQNMEF--LRGVYAFMQVSRSSVSHVKIDSPVF-RLHTNATVIL 193
            |..:.|:.:.:.:|..........|.|  :.|..:|:|        .:.|..:| |||...|...
 Worm     3 AQALPQHSASSNKTGGSPGARVPRMVFAEIVGTLSFLQ--------PQADDDIFDRLHYYYTTTF 59

  Fly   194 LITFSIAVTTRQYVGNPIDC---VHTRDIPEDVLNTYCWIHSTYTVVDAFMKKQGSEVPFPGVHN 255
            |:..::.::.:.:.|.||:|   ...:...||....|||..:||  |.||     .:...|.|.|
 Worm    60 LLLTAVLISLKMFGGRPIECWLPAEYKSSWEDYTEMYCWARNTY--VTAF-----EDDNLPEVVN 117

  Fly   256 SQGRGPLTIKHTKYYQWVAFTLFFQAILFYTPRWLWKSWEGGKIHALIMDLDIGICSE------A 314
            .:      .....|||||.|.|.:.|..||.|..:|:.:. .|....:.|: :|..::      .
 Worm   118 RE------YTMVSYYQWVPFFLVYVAFSFYAPCLIWRLFY-DKSGIRLKDI-MGFANDKANVVPT 174

  Fly   315 EKKQKKKLLLDYLWE----------------------NLRYH-NWWAYRYYVCELLALINVIGQM 356
            ::....:.|..:|..                      |:||: ::..|.|...:.|.|:||:.||
 Worm   175 QRTANIRGLSAHLSSVFKHRFRIGEKHPYHHKVFRIFNVRYYESYLTYLYLAIKCLFLMNVLTQM 239

  Fly   357 FLMNRFFD---GEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICI 418
            :.|:||.:   ..:..:|:.....|....::..:     ||.:|.|. .:....|.|::|...|:
 Worm   240 YFMSRFLELDSHRYYGYGIFYDLIMGKGWKESSN-----FPVVTYCD-MQIRILGHVQRHTVQCV 298

  Fly   419 LPLNVVNEKIYIFLWFWFI---LLTFLTLLTLIYRVVIIFSPRMRVYLFRMRFRLV-------RR 473
            |.:|:..|||:..||.|:.   |::|.::|:.|: ..|.|:.|.:....|:....|       ::
 Worm   299 LVINIFTEKIFFILWLWYTMLSLISFGSILSWIF-ASIPFNQRRQFIARRLELADVNFEKSRFKQ 362

  Fly   474 DAIEIIVRRSKMGDWFLLYLLGENIDTVIFRDVVQDLANRL----GH 516
            :..|.:....|:...|:|.::..:...::..|:|..:.::.    ||
 Worm   363 ELDEFVRDYIKIDGIFVLRMITIHSGILMCTDIVDTMWDQFLQESGH 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shakB	NP_608410.2	Innexin	179..514	CDD:279248	88/380 (23%)
inx-20	NP_001251235.1	Innexin	45..403	CDD:279248	87/379 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I3133
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I3152
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28980
OrthoDB	1	1.010	-	-		D323554at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4755
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11893
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X282
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.080