Protein Alignment shakB and unc-9

DIOPT Version :9

• Sequence 1: NP_608410.2
• Gene: shakB / 33062
• FlyBaseID: FBgn0085387
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_741917.1
• Gene: unc-9 / 181443
• WormBaseID: WBGene00006749
• Length: 386
• Species: Caenorhabditis elegans
• Alignment Length: 433
• Identity: 110/433 - (25%)
• Similarity: 181/433 - (41%)
• Gaps: 115/433 - (26%)

  Fly   162 VYAFMQVSRSSVSHVKIDSPVFRLHTNATVILLITFSIAVTTRQYVGNPIDC----VHTRDIPED 222
            :|.|....:|...||. |..:.:|:...|..::..|:|.|:.:||||.||.|    ..|..: |.
 Worm     5 LYYFASAVKSIQFHVD-DDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPM-EQ 67

  Fly   223 VLNTYCWIHSTYTVVDAFMKKQGSEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAILFYTP 287
            ....|||:.:||     |:... ..:|    ||...|   ..:...|||||.|.|..:|:|||.|
 Worm    68 YTENYCWVQNTY-----FLPLH-DYIP----HNYAER---ENRQIGYYQWVPFVLALEALLFYVP 119

  Fly   288 RWLWK--SWEGGKIH----------ALIMDLD----------------IGICSEAEKKQKKKLL- 323
            ..:|:  ||:.| ||          :.::||:                :.:..:.....:.|||
 Worm   120 TIVWRLLSWQSG-IHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLKLLN 183

  Fly   324 -----------LDYLWENLRYHNWWAYRYYVCELLALINVIGQMFLMNRFFDGEFITFGLKVIDY 377
                       :.:|             |...::|..:|::||:||:|.|.......:||:|::.
 Worm   184 LIICTRSSGAAVTFL-------------YISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLND 235

  Fly   378 METDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEKIYIFLWFWFILLTFL 442
            :...:|......   |||:|.|. |:....|.|.:|...|:|.:|:.||||::|||||:.||...
 Worm   236 LMNGREWEESGH---FPRVTLCD-FEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGA 296

  Fly   443 TLLTLIYRVVIIFSPRMRV-----YLF--------------RMRFRLVRRDAIEIIVRRSKMGDW 488
            ||.:|.|.:.|...|..::     ||.              |..|..:|:|.:
 Worm   297 TLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGV------------ 349

  Fly   489 FLLYLLGENIDTVIFRDVVQDLANRLGHNQHHRVPGLKGEIQD 531
            |||.::..:...:...::.:.|.|....|:       :|::.|
 Worm   350 FLLRMVATHAGELPCYELAKTLWNNYCDNK-------EGKMHD 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shakB	NP_608410.2	Innexin	179..514	CDD:279248	102/397 (26%)
unc-9	NP_741917.1	Innexin	22..374	CDD:395704	100/395 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I3133
eggNOG	1	0.900	-	-		E1_2BWHM
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I3152
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28980
OrthoDB	1	1.010	-	-		D323554at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4755
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11893
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X282
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.980