Protein Alignment shakB and inx-2

DIOPT Version :9

• Sequence 1: NP_608410.2
• Gene: shakB / 33062
• FlyBaseID: FBgn0085387
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_509885.1
• Gene: inx-2 / 181318
• WormBaseID: WBGene00002124
• Length: 419
• Species: Caenorhabditis elegans
• Alignment Length: 304
• Identity: 81/304 - (26%)
• Similarity: 138/304 - (45%)
• Gaps: 52/304 - (17%)

  Fly   184 RLHTNATVILLITFSIAVTTRQYVGNPIDCVHTRDIP---EDVLNTYCWIHSTYTVVDAFMKKQG 245
            |::...|..:|:..::|::.:||.|.||.|...|:..   :..::.:|:|.:||.|      ..|
 Worm    30 RVNAWFTPFVLVAMTLAISCKQYFGQPIKCWTPREFSGSWDGYVHDFCFIENTYFV------PNG 88

  Fly   246 SEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAILFYTPRWLWKSWEGGKIHALIMDLDI-- 308
            :||      ..:.||.   :|..||:||...|.|||.:|..|..||..:.......|...|..
 Worm    89 TEV------TDEARGG---RHINYYRWVPLVLLFQAAMFVLPYHLWNLFHKRTTINLKGSLRFFE 144

  Fly   309 GICSEAEKKQKKKLLLDYLWENL--------RYHNWWA-YRYYVCELLALINVIGQMFLMNRFFD 364
            |...:.|..|..:.....:|..|        :.:.:.| ..|::.:|..::|.|.||.|:..|.|
 Worm   145 GALKKLEPAQACESFAGEIWNRLSDIRNSSNKLYGFQATINYFLLKLGFIVNCILQMVLLKHFLD 209

  Fly   365 GEFITFG---LKVIDYMET-DQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVN 425
            .:...:|   |..:::..| ::||.      ||||:..|. ||..:.|:..:|...||:.||::.
 Worm   210 VDDYFWGFFHLWNVEFKGTAEKEDS------IFPRIVLCD-FKVRNLGQQHQHTVSCIMILNMII 267

  Fly   426 EKIYIFLWFWFILLTFLTLLTLIYRVVIIFSPRMRVYLFRMRFR 469
            ||:||..:||.|.:..:|...:|:            :.|::.||
 Worm   268 EKLYICFYFWLIFVFVVTTAGMIH------------FAFQILFR 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shakB	NP_608410.2	Innexin	179..514	CDD:279248	81/304 (27%)
inx-2	NP_509885.1	Innexin	26..358	CDD:279248	81/304 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I3133
eggNOG	1	0.900	-	-		E1_2BWHM
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I3152
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28980
OrthoDB	1	1.010	-	-		D323554at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4755
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11893
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.940