Protein Alignment shakB and inx-5

DIOPT Version :9

• Sequence 1: NP_608410.2
• Gene: shakB / 33062
• FlyBaseID: FBgn0085387
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_509403.2
• Gene: inx-5 / 181086
• WormBaseID: WBGene00002127
• Length: 447
• Species: Caenorhabditis elegans
• Alignment Length: 371
• Identity: 93/371 - (25%)
• Similarity: 149/371 - (40%)
• Gaps: 97/371 - (26%)

  Fly   194 LITFS-IAVTTRQYVGNPIDCVHTRDIP-------EDVLNTYCWIHSTYTVVDAFMKKQGSEVPF 250
            |:.|| |.:...||||.||.|.    :|       |....|||:|..||.:
 Worm    33 LLGFSAIMMAASQYVGRPIQCW----VPAQFTRTWEKYAETYCFIKGTYFL-------------- 79

  Fly   251 PGVHNSQGRGPLT--------IKHTKYYQWVAFTLFFQAILFYTPRWLWKSWEGG---KIHALIM 304
            ||...|:|...:|        .....||||:...|..||.|||.|..:|:::...   ||.
 Worm    80 PGAFASEGEMSVTSPDDAVTATPQVGYYQWIPIVLVLQAFLFYLPSIIWRTFNESCELKIK---- 140

  Fly   305 DLDIGICSEAEKKQKKKLLLD---------YLWENLRYHN----------------WWAYRYYVC 344
              ::...|||.:|.|..:..|         |.::.|.:.|                :....|.:.
 Worm   141 --ELAAVSEASRKIKSNMSDDQVKATKFGRYFFKKLNFRNESPVFKETGSVVASGKFLPALYLLV 203

  Fly   345 ELLALINVIGQMFLMNRFFDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGE 409
            ::|.|.|::.|.:::..|.:.:...:|.:....:...:|.....   ||||:|.|. |.......
 Worm   204 KILYLANIVLQFWILTYFLETKSWMWGWQTFQDLMAGREWETTG---IFPRVTMCD-FSIMDLTS 264

  Fly   410 VEKHDAICILPLNVVNEKIYIFLWFWFILLTFLTLLTLIYRVVI----------IFS-----PRM 459
            |..|...|::.:|::.||:|:|.|||.:.:..||:.:|.|..||          |:|     |..
 Worm   265 VHDHSIQCVIVINMLAEKVYVFFWFWLLFVGLLTVCSLAYWAVIYMLQSVGRNFIYSYLQQTPEF 329

  Fly   460 RVYLFRMRF-------RLVRRDAIEI--IVRRSKMGDWFLLYLLGE 496
            :....|..|       :.:..|.:.|  :|:::. ||.|...:|||
 Worm   330 QTEQERGSFVPANFVDKCLTPDGVFISRLVQQNS-GDLFTSIMLGE 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shakB	NP_608410.2	Innexin	179..514	CDD:279248	93/371 (25%)
inx-5	NP_509403.2	Innexin	20..379	CDD:279248	93/371 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I3133
eggNOG	1	0.900	-	-		E1_2BWHM
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I3152
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28980
OrthoDB	1	1.010	-	-		D323554at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4755
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11893
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X282
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.980