Protein Alignment shakB and inx-6

DIOPT Version :9

• Sequence 1: NP_608410.2
• Gene: shakB / 33062
• FlyBaseID: FBgn0085387
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_502435.1
• Gene: inx-6 / 178231
• WormBaseID: WBGene00002128
• Length: 389
• Species: Caenorhabditis elegans
• Alignment Length: 391
• Identity: 89/391 - (22%)
• Similarity: 161/391 - (41%)
• Gaps: 83/391 - (21%)

  Fly   184 RLHTNATVILLITFSIAVTTRQYVGNPIDCVHTRDIPE---DVLNTYCWIHSTYTV-VD---AFM 241
            ||::..||::|...|..:.:..::|:||.|........   :.:|.||::|.||.| :|   ||.
 Worm    29 RLNSRVTVVILAVSSALLLSSHFIGDPITCWTPAQFNAQWVNFVNQYCFVHGTYFVPLDQQLAFE 93

  Fly   242 KKQGSEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAILFYTPRWLWK---SWEGGKIHALI 303
            :::.::|..                 :|||||.:....||.|||.||::||   ::.|..:.|.:
 Worm    94 EEERTKVSI-----------------QYYQWVPYVFALQAFLFYIPRFIWKAMIAYSGYDLAAAV 141

  Fly   304 MDLDIGICSEAEKKQKKKLLLD--------YLWENLRY------HNWWAYRYYVCELLALINVIG 354
            ..:|.......:|..|.|..|.        |:|:.:|.      .| .|..|.:..:...:|...
 Worm   142 KYVDRFWSENRDKDDKFKTRLAAFEGRPSVYIWDGIRLARKKRSRN-MALFYTLSTVWQAVNAWI 205

  Fly   355 QMFLMNRFFDGEFIT-FGLKVI-------DYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVE 411
            |.:::.:..|....| :|..::       |:..|..          |||:..|.|.: .....|:
 Worm   206 QFYILTQLLDSSIYTLWGPSILGDLLQGNDWQTTGH----------FPRIVHCDFNR-RRPASVQ 259

  Fly   412 KHDAICILPLNVVNEKIYIFLWFWFILLTFLTLLTLIYRVVIIFS-----PRMRVYLFR------ 465
            ....:|:|.||:..||::||||||.:.:..::.:.....:..:.:     ..::.||..
 Worm   260 LDTVLCVLTLNIYYEKLFIFLWFWLVFVAVVSTVNCFKWIYYLCNKTKAQKTIKNYLSTAPIKST 324

  Fly   466 ----MRFRLVRRDAIEIIVRRS-KMGDWFLLYLLGENIDTVIFRDVVQDLANRLGHNQHHRVPGL 525
                ..|..:..|.:.|:.:.: .:||....||      |:..|::.||......:....|.|.:
 Worm   325 ISDDQFFSALGEDGLFIMDQMALNLGDIPASYL------TISMRNICQDFIESEDYIDEERTPFV 383

  Fly   526 K 526
            |
 Worm   384 K 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shakB	NP_608410.2	Innexin	179..514	CDD:279248	86/377 (23%)
inx-6	NP_502435.1	Innexin	25..364	CDD:395704	84/369 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I3133
eggNOG	1	0.900	-	-		E1_2BWHM
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I3152
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28980
OrthoDB	1	1.010	-	-		D323554at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4755
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11893
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X282
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.980