Protein Alignment shakB and inx-15

DIOPT Version :9

• Sequence 1: NP_608410.2
• Gene: shakB / 33062
• FlyBaseID: FBgn0085387
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_491313.1
• Gene: inx-15 / 172004
• WormBaseID: WBGene00002137
• Length: 382
• Species: Caenorhabditis elegans
• Alignment Length: 418
• Identity: 103/418 - (24%)
• Similarity: 173/418 - (41%)
• Gaps: 100/418 - (23%)

  Fly   156 MEFLRGVYAFMQVSRSSVSHVKIDSPVFRLHTNATVILLITFSIAVTTRQYVGNPIDCVHTRDIP 220
            |||:..:.....|.|..      |..:.||:...:..:....::.:....|.|..|.|....:..
 Worm     1 MEFVVNLVTQYTVQRHE------DDFIDRLNFQYSAYVFALSALVIGYHTYFGRAISCWTPAEFK 59

  Fly   221 ---EDVLNTYCWIHSTYTVVDAFMKKQGSEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAI 282
               .:....||.|.:||     ::..:...:| |..:..:       |...|||||.|.|.|.|.
 Worm    60 GGWNEYTTDYCLIENTY-----YVPLEDPNMP-PERYREE-------KELSYYQWVQFILVFLAF 111

  Fly   283 LFYTPRWLWKS---WEGGKIHALI-----MD-LDIG--------ICSEAEK---KQKKKLLLDYL 327
            |||.|...|.:   |.|.::.|::     :| .|:|        |.|..:|   :|.:|..:. |
 Worm   112 LFYLPYLYWSTVNWWSGLQVKAVVDVACNLDKTDVGKRNAGIEKIASHLKKYIDRQGRKSPIP-L 175

  Fly   328 WENLRYHNWWAYRYYVCELLALINVIGQMFLMNRF--FD-GEFIT----FGLKVIDYMETDQEDR 385
            ..|:...||.::.|.:.:.|.|:|:|.||||::.|  || .:||:    ||...|
 Worm   176 IPNIIGRNWVSFNYILTKFLFLVNLIAQMFLIHFFLGFDLDDFISLRVGFGSNWI---------- 230

  Fly   386 MDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEKIYIFLWFWFILLTFLTLLTLIYR 450
               ...||||.|.|. |:....|.::|:...|:|.:|::|||:::.|::|.|.|.|||:..|
 Worm   231 ---ANGIFPRQTMCD-FEIRKKGSIQKYSVQCVLSMNMLNEKVFLALFYWIIALFFLTVWNL--- 288

  Fly   451 VVIIFSPRMRVYLFRMRFRLVRR----------------DAIEIIVR--RSKMGDW--------- 488
                |:.....:....|...|||                :.:.::.|  .:...|:
 Worm   289 ----FTSFQHFFHASSRKEFVRRMLSAGGHTLTDGGHGEEKVPLVERPDGTYSNDYNRVLSINPD 349

  Fly   489 --FLLYLLGENIDTVIFRDVVQDLANRL 514
              .:|:|:.:|....:.::||..|..:|
 Worm   350 IVVVLHLIAKNAGDNVCQNVVDMLFQKL 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shakB	NP_608410.2	Innexin	179..514	CDD:279248	97/393 (25%)
inx-15	NP_491313.1	Innexin	18..377	CDD:279248	97/393 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I3133
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I3152
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28980
OrthoDB	1	1.010	-	-		D323554at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4755
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11893
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X282
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.080