Protein Alignment shakB and inx-12

DIOPT Version :9

• Sequence 1: NP_608410.2
• Gene: shakB / 33062
• FlyBaseID: FBgn0085387
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: NP_491213.1
• Gene: inx-12 / 171944
• WormBaseID: WBGene00002134
• Length: 408
• Species: Caenorhabditis elegans
• Alignment Length: 324
• Identity: 86/324 - (26%)
• Similarity: 144/324 - (44%)
• Gaps: 59/324 - (18%)

  Fly   166 MQVSRSSVSHVKIDSP------VFRLHTNATVILLITFSIAVTTRQYVGNPIDC---VHTRDIPE 221
            |.|.::.:|.|   ||      |.:|:..||.|.|:..|..:|...:||:||||   .:.:....
 Worm     1 MNVIQNLLSAV---SPQPDGDFVDKLNYCATTIGLVLASAFITGWSFVGSPIDCWFPAYYKGWWA 62

  Fly   222 DVLNTYCWIHSTYTVVDAFMKKQGSEVPFPGVHN-----SQGRGPLTIKHTK---YYQWVAFTLF 278
            :....||::.:|:.|..:..|.:.|       :|     :..:...::|.|.   |||||.|.|.
 Worm    63 EYALDYCYVQNTFFVPFSEDKAERS-------YNWEQLVADKQNTTSLKQTNQIGYYQWVPFILA 120

  Fly   279 FQAILFYTPRWLWK---SWEGGKIHALIMDLDIGICSEAE------------------KKQKKKL 322
            .||:|||.|..:|:   ...|..:.:|     ...|:..|                  :|:.:.|
 Worm   121 LQAMLFYFPVVIWRLFYGMAGQNVTSL-----CNTCTATEGNEESRKGTITTIAGYISQKRHRNL 180

  Fly   323 LLDYL--WENLRYHNWWAYRYYVCELLALINVIGQMFLMNRFFDGEFITFGLKVIDYMETDQEDR 385
            ::..|  ::|....:.....|...:.|.||||:.|..|:.|....:...:|.:|...:.:..|
 Worm   181 IVKQLSGFQNRANGSAVITSYLFMKALFLINVLFQFVLLKRMLGVDSYFWGAEVTSDLWSGNE-- 243

  Fly   386 MDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEKIYIFLWFWFILLTFLTLLTLIY 449
             .|....|||:|.|. ::..:...:.||...|:|.:|:.||||::.||:|...||.:|:...||
 Worm   244 -WPETGNFPRVTMCE-YEVRNLDNIHKHSVQCVLMINMFNEKIFVALWWWLCFLTVVTITNTIY 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shakB	NP_608410.2	Innexin	179..514	CDD:279248	82/311 (26%)
inx-12	NP_491213.1	Innexin	18..377	CDD:279248	80/304 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I3133
eggNOG	1	0.900	-	-		E1_2BWHM
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I3152
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28980
OrthoDB	1	1.010	-	-		D323554at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4755
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11893
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X282
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.980