Sequence 1: | NP_001285501.1 | Gene: | run / 33059 | FlyBaseID: | FBgn0003300 | Length: | 510 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001019801.3 | Gene: | RUNX2 / 860 | HGNCID: | 10472 | Length: | 521 | Species: | Homo sapiens |
Alignment Length: | 560 | Identity: | 173/560 - (30%) |
---|---|---|---|
Similarity: | 233/560 - (41%) | Gaps: | 173/560 - (30%) |
- Green bases have known domain annotations that are detailed below.
Fly 15 QVLAAAAAAAAAAAAAVAQGPGPQ-QSSNATTASAIAINPAQSLANTSTHSASSTGSSTPDLSTN 78
Fly 79 NTSSSSNATTSPQNSAKMPSSMTDMFASLHEMLQEYHGELAQTGSPSILCSALPNHWRSNKSLPG 143
Fly 144 AFKVIALDDVPDGTLVSIKCGNDENYCGELRNCTTTMKNQVAKFNDLRFVGRSGRGKSFTLTITI 208
Fly 209 ATYPVQIASYSKAIKVTVDGPREPR--------SKQSY---------GYPH-------------- 242
Fly 243 -----PGAFNP-----------FMLNPAW-LDAAYMTYGYADYFRHQAAAQAAQVHHPALAKSSA 290
Fly 291 SSV-SPNPNPSVATSSSSAVQ--PSEYPHPAAAVAAAAGQPAAM-MPSPPGAAPATPYAIP-QFP 350
Fly 351 FNHVAAAAAAKAATPHAFHPYNFA----AAAGLR-ARNAALHHQSEPVHVSPASSRPSSSSPTQQ 410
Fly 411 HVLLKLNTSIETSSIHEQSASDGDSDDEQIDVVKSEFDLDKSLDVAPLRM--RCDL--KAPSAMK 471
Fly 472 PLYHESGPGAVAN-SRQPSPETTTKIKSAAVQQKTVWRPY 510 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
run | NP_001285501.1 | Runt | 114..235 | CDD:279225 | 84/128 (66%) |
RUNX2 | NP_001019801.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 18..59 | ||
polyglutamine repeat | 49..71 | 173/560 (31%) | |||
polyalanine repeat | 73..89 | 13/15 (87%) | |||
Runt | 109..230 | CDD:307137 | 86/182 (47%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 222..340 | 28/138 (20%) | |||
Required for interaction with FOXO1. /evidence=ECO:0000250 | 242..258 | 2/15 (13%) | |||
Herpes_BLLF1 | <266..481 | CDD:330317 | 49/258 (19%) | ||
Interaction with KAT6A. /evidence=ECO:0000250 | 336..439 | 24/113 (21%) | |||
Interaction with KAT6B. /evidence=ECO:0000269|PubMed:11965546 | 374..468 | 23/116 (20%) | |||
RunxI | 430..521 | CDD:312115 | 26/114 (23%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 460..521 | 16/63 (25%) | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165142095 | |
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 1 | 1.050 | 203 | 1.000 | Inparanoid score | I3751 |
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 1 | 1.000 | - | - | FOG0000993 | |
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 1 | 1.100 | - | - | O | PTHR11950 |
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3284 |
SonicParanoid | 1 | 1.000 | - | - | X738 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
6 | 6.110 |