Protein Alignment run and runx3

DIOPT Version :9

• Sequence 1: NP_001285501.1
• Gene: run / 33059
• FlyBaseID: FBgn0003300
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001349273.1
• Gene: runx3 / 58127
• ZFINID: ZDB-GENE-000605-2
• Length: 438
• Species: Danio rerio
• Alignment Length: 534
• Identity: 155/534 - (29%)
• Similarity: 217/534 - (40%)
• Gaps: 160/534 - (29%)

  Fly    40 SSNATTASAIAINPAQSLANTSTHSASSTGSSTPDLSTNNTSSSSNATTSPQNSAKMPSSMTDMF 104
            :||:...:..:.:|  ||....:.|...|..|........|.|.|.:...|..|.:...|
Zfish     2 ASNSIFDTFSSYSP--SLLRDPSTSRRFTPPSASFPCAKVTESQSMSAPGPLRSGRPVES----- 59

  Fly   105 ASLHEMLQEYHGELAQTGSPSILCSALPNHWRSNKSLPGAFKVIALDDVPDGTLVSIKCGNDENY 169
            .|:.::|.::.|||.:|.||:.|||.||:|||.||:||.||||:||.||||||||::..||||||
Zfish    60 RSVVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTLVTVMAGNDENY 124

  Fly   170 CGELRNCTTTMKNQVAKFNDLRFVGRSGRGKSFTLTITIATYPVQIASYSKAIKVTVDGPREPRS 234
            ..||||.:..||||||:|||||||||||||||||||||:.|.|.|:|:|.:|||||||||||||.
Zfish   125 SAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTGPPQVATYHRAIKVTVDGPREPRR 189

  Fly   235 KQSYGYPHPGAFNPFMLNPAWLDAAYMTYG--YADYFRHQAAA----------QAAQVHHPALAK 287
            .:              :.|   |..:..:.  .:|..|.|.|:          :..|.|:
Zfish   190 HR--------------VKP---DDPHKQFSDRLSDIERFQRASLRMNPGNGTTRPHQTHY----- 232

  Fly   288 SSASSVSPNPNPSVATSSSSAVQPSEYPHPAAAVAAAAG----------QPAAMMPSPPGAAPAT 342
                      :|| :|:....:.|.:...|.........          |.....||      .:
Zfish   233 ----------SPS-STTQIPGLWPDQIDPPTLKTCKVEDDLRWTSTDLFQQRTSFPS------LS 280

  Fly   343 PYAIPQFPFNH-----------------VAAAAAAKAATPHAFHPYNFAAAAGLRARNAALHHQS 390
            |...|:|..:|                 :...:.|...|...:|.|......|.:.:|:.....|
Zfish   281 PLTAPRFSDSHMHYPSHFTYSANPSSTGIGGLSVAGMPTSSRYHTYLPPPYPGNQNQNSHFQTNS 345

  Fly   391 EPVHV---------------SPASSRPSSSSPTQQHVLLKL---------NTSIETSSIHEQSAS 431
            .|.|:               :..|......|||:.......         |.::..:::..|  |
Zfish   346 SPYHLYYGTGSGSYQFSMIPTGGSGSGGDRSPTRMLTSCTAAGGAAGNTGNNNLINANLGNQ--S 408

  Fly   432 DGDSDDEQIDVVKSEFDLDKSLDVAPLRMRCDLKAPSAMKPLYHESGPGAVANSRQPSPETTTKI 496
            ||             .|.|.|                      |.:.|.|::.|        |:|
Zfish   409 DG-------------VDADGS----------------------HSNSPTAMSAS--------TRI 430

  Fly   497 KSAAVQQKTVWRPY 510
                  .::|||||
Zfish   431 ------DESVWRPY 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
run	NP_001285501.1	Runt	114..235	CDD:279225	87/120 (73%)
runx3	NP_001349273.1	Runt	69..190	CDD:307137	87/120 (73%)
		RunxI	334..438	CDD:312115	25/154 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575056
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11950
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X738
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.030