Protein Alignment run and runx3

DIOPT Version :10

• Sequence 1: NP_523424.2
• Gene: run / 33059
• FlyBaseID: FBgn0003300
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001349273.1
• Gene: runx3 / 58127
• ZFINID: ZDB-GENE-000605-2
• Length: 438
• Species: Danio rerio
• Alignment Length: 534
• Identity: 155/534 - (29%)
• Similarity: 217/534 - (40%)
• Gaps: 160/534 - (29%)

  Fly    40 SSNATTASAIAINPAQSLANTSTHSASSTGSSTPDLSTNNTSSSSNATTSPQNSAKMPSSMTDMF 104
            :||:...:..:.:|  ||....:.|...|..|........|.|.|.:...|..|.:...|
Zfish     2 ASNSIFDTFSSYSP--SLLRDPSTSRRFTPPSASFPCAKVTESQSMSAPGPLRSGRPVES----- 59

  Fly   105 ASLHEMLQEYHGELAQTGSPSILCSALPNHWRSNKSLPGAFKVIALDDVPDGTLVSIKCGNDENY 169
            .|:.::|.::.|||.:|.||:.|||.||:|||.||:||.||||:||.||||||||::..||||||
Zfish    60 RSVVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTLVTVMAGNDENY 124

  Fly   170 CGELRNCTTTMKNQVAKFNDLRFVGRSGRGKSFTLTITIATYPVQIASYSKAIKVTVDGPREPRS 234
            ..||||.:..||||||:|||||||||||||||||||||:.|.|.|:|:|.:|||||||||||||.
Zfish   125 SAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTGPPQVATYHRAIKVTVDGPREPRR 189

  Fly   235 KQSYGYPHPGAFNPFMLNPAWLDAAYMTYG--YADYFRHQAAA----------QAAQVHHPALAK 287
            .:              :.|   |..:..:.  .:|..|.|.|:          :..|.|:
Zfish   190 HR--------------VKP---DDPHKQFSDRLSDIERFQRASLRMNPGNGTTRPHQTHY----- 232

  Fly   288 SSASSVSPNPNPSVATSSSSAVQPSEYPHPAAAVAAAAG----------QPAAMMPSPPGAAPAT 342
                      :|| :|:....:.|.:...|.........          |.....||      .:
Zfish   233 ----------SPS-STTQIPGLWPDQIDPPTLKTCKVEDDLRWTSTDLFQQRTSFPS------LS 280

  Fly   343 PYAIPQFPFNH-----------------VAAAAAAKAATPHAFHPYNFAAAAGLRARNAALHHQS 390
            |...|:|..:|                 :...:.|...|...:|.|......|.:.:|:.....|
Zfish   281 PLTAPRFSDSHMHYPSHFTYSANPSSTGIGGLSVAGMPTSSRYHTYLPPPYPGNQNQNSHFQTNS 345

  Fly   391 EPVHV---------------SPASSRPSSSSPTQQHVLLKL---------NTSIETSSIHEQSAS 431
            .|.|:               :..|......|||:.......         |.::..:::..|  |
Zfish   346 SPYHLYYGTGSGSYQFSMIPTGGSGSGGDRSPTRMLTSCTAAGGAAGNTGNNNLINANLGNQ--S 408

  Fly   432 DGDSDDEQIDVVKSEFDLDKSLDVAPLRMRCDLKAPSAMKPLYHESGPGAVANSRQPSPETTTKI 496
            ||             .|.|.|                      |.:.|.|::.|        |:|
Zfish   409 DG-------------VDADGS----------------------HSNSPTAMSAS--------TRI 430

  Fly   497 KSAAVQQKTVWRPY 510
                  .::|||||
Zfish   431 ------DESVWRPY 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
run	NP_523424.2	Runt	107..235	CDD:459963	88/127 (69%)
runx3	NP_001349273.1	Runt	62..190	CDD:459963	88/127 (69%)
		RunxI	334..438	CDD:430037	25/154 (16%)