Protein Alignment run and RunxA

DIOPT Version :10

• Sequence 1: NP_523424.2
• Gene: run / 33059
• FlyBaseID: FBgn0003300
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001259747.1
• Gene: RunxA / 4379817
• FlyBaseID: FBgn0083981
• Length: 663
• Species: Drosophila melanogaster
• Alignment Length: 469
• Identity: 161/469 - (34%)
• Similarity: 223/469 - (47%)
• Gaps: 123/469 - (26%)

  Fly    40 SSNATTASAIAINPAQSLANTSTHSASST----GSSTPDLSTNNTSSSSNATTSPQNSAKMPSSM 100
            |||:|.::| ..|...:..|.:|.|.::|    |||..:.|.||.:||.|.:.:.||:...|:.:
  Fly     7 SSNSTASNA-NNNNNNTANNNNTSSNNNTTNTNGSSNNNTSGNNNNSSGNNSNTEQNTPPTPAQL 70

  Fly   101 ---------TDMFA--SLHEMLQEYHGELAQTGSPSILCSALPNHWRSNKSLPGAFKVIALDDVP 154
                     :|:.|  :|.:.|.|:.|||.:|.||..:|:.||.||||||:||.||||::|.|:.
  Fly    71 LNEAYTKMTSDILAERTLGDFLTEHPGELIRTSSPLFVCTVLPPHWRSNKTLPVAFKVVSLGDIM 135

  Fly   155 DGTLVSIKCGNDENYCGELRNCTTTMKNQVAKFNDLRFVGRSGRGKSFTLTITIATYPVQIASYS 219
            |||:|:::.|||||||.||||||..||||||||||||||||||||||||||||::|.|..||:|:
  Fly   136 DGTMVTVRAGNDENYCAELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTITVSTNPPHIATYN 200

  Fly   220 KAIKVTVDGPREPRSK---------QSYGY------------PHPGAFNPFMLNPAWLDAAYMTY 263
            ||||||||||||||||         |.:.:            |..|...|.:.|.......:..|
  Fly   201 KAIKVTVDGPREPRSKTMLSLLGQQQQFHFAFGQRPFHFSTDPLSGFRMPPIGNCQSASNTHWGY 265

  Fly   264 G-----YADYFRHQAAAQ-----AAQVHHPALAKSSASSVSPN----------------PNPSVA 302
            |     |:.|......:.     :||.::|||..:.:|:...|                |:.:.:
  Fly   266 GSAASAYSPYLASSGLSSCTTPTSAQFNNPALGFTCSSNDQSNNQDFGGATNRDCVPMLPDSTAS 330

  Fly   303 ----------------------------TSSSSAVQPSEYPHPAAAVAAAAGQPAAMMPSPPGAA 339
                                        ||.||.|..:.  ...:|.|..||..|.......|.|
  Fly   331 DLDQHLSSLVGSTSGQMTHHSLLGAGGQTSISSTVNGAS--GGGSAGAGTAGGGAGSGGGAGGGA 393

  Fly   340 PATPYAIPQFPFNHVAAAAAAKAATPHAFHPYNFAAAAGLRARNAALHHQSEPVHVSPASSRPSS 404
            ......:|::..|              |.:.||..::            |:.|..:|.:|   .:
  Fly   394 GGNSILVPRYHTN--------------ASNEYNVHSS------------QNGPRSLSDSS---QA 429

  Fly   405 SSPTQQHVLLKLNT 418
            .||.|:. ||..||
  Fly   430 ESPVQED-LLTTNT 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
run	NP_523424.2	Runt	107..235	CDD:459963	90/127 (71%)
RunxA	NP_001259747.1	Runt	88..216	CDD:459963	90/127 (71%)