Protein Alignment run and LOC1273456

DIOPT Version :10

• Sequence 1: NP_523424.2
• Gene: run / 33059
• FlyBaseID: FBgn0003300
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_061506989.1
• Gene: LOC1273456 / 1273456
• VectorBaseID: AGAMI1_009727
• Length: 705
• Species: Anopheles gambiae
• Alignment Length: 714
• Identity: 200/714 - (28%)
• Similarity: 262/714 - (36%)
• Gaps: 277/714 - (38%)

  Fly    34 GPGPQQSSNATTASAIAINPAQSLANTSTHSASSTGSSTPDLSTNNTSSSSNATTSPQNSAKMPS 98
            |.|..::..||:.......|..|..|     :..||...|  |.||  ..|:||    :...:|:
Mosquito    32 GTGMLETGTATSGGDAGTQPGGSCRN-----SGGTGVLQP--SQNN--GGSHAT----DDNAIPA 83

  Fly    99 SMTDMFASLHEMLQEYHGELAQTGSPSILCSALPNHWRSNKSLPGAFKVIALDDVPDGTLVSIKC 163
            .:..|...:.|..|:|.|||.:|.||..|||||||||||||:||.|||||:|.||.|||:|:|:.
Mosquito    84 DLRWMERMVMEAEQQYPGELVRTDSPYFLCSALPNHWRSNKTLPSAFKVISLGDVSDGTMVTIRA 148

  Fly   164 GNDENYCGELRNCTTTMKNQVAKFNDLRFVGRSGRGKSFTLTITIATYPVQIASYSKAIKVTVDG 228
            |||||:|.||||||..|:|||||||||||||||||||||||||||.|...|:.:|.|||||||||
Mosquito   149 GNDENFCAELRNCTAVMRNQVAKFNDLRFVGRSGRGKSFTLTITICTTMPQVTTYCKAIKVTVDG 213

  Fly   229 PREPRSKQSYGYPHPGAFNPFMLNPAWLDAAY--------------------------------- 260
            |||||||.:.....|...:.|:..||:....|
Mosquito   214 PREPRSKTNMPQMRPPPLHRFLEQPAFNHHHYPGRPGSFGGTGGSNTGSSSSNNNNNNNGGGLGS 278

  Fly   261 ----------------------MTYGYADYFRHQAAAQAA-----QVHHP--------------- 283
                                  ...|.:....:.|.:...     ..|||
Mosquito   279 NGLGTGSTGSLGGGGTAGTGHGNGNGKSSSVNYSAVSSTGSTTNLHTHHPHHHHHHHHHGSGGGG 343

  Fly   284 ------ALAKSSASSVSPNPN-------------------------------------------- 298
                  |:..|:.||....||
Mosquito   344 GGGGNMAINTSAESSSDYKPNLAFSDYTSATDWTNGLVGAPSSTSYMNTFSPLQASPPSYVAYDS 408

  Fly   299 ------PSVATSSSSAV----QP-SEY--------PHPAAAVAAAA--------------GQPAA 330
                  |:.:.::|..|    || .:|        |.||..|||.|              ||.||
Mosquito   409 CPMVDHPNYSLTASGVVLDNLQPYQDYYGLSGPPPPPPAPTVAAVAPPTGTSTVQTGPLGGQLAA 473

  Fly   331 ---MMPSPPG---AAPATPYAIPQFP--------------------FNHVAAAAAAKAA------ 363
               ...|..|   .|.||....|.:|                    :||.||||||.|.
Mosquito   474 GGSSYVSKTGELVEAAATTTTYPSYPHHTQWTNGYHGSYHHHHHHQYNHPAAAAAASAGGCASSL 538

  Fly   364 -----TPHAFHPYNFAAAAGLRARNAALHHQSEPVHVSPA-SSRPSSSSPTQQHVLLKLNTSIET 422
                 :|.:|||.....||                   || ||.|:...|....:..::.:::..
Mosquito   539 AVAAQSPVSFHPPVATVAA-------------------PAPSSVPAPPPPPPMVLCPQMFSTVNQ 584

  Fly   423 SSIHEQSASDG-DSDDEQIDVVKSEFDLD-------KSLDVAPLRMRCDLKAPSA-----MKPLY 474
            :.||......| |..:.......:.|.::       :|:...|:  ...|.|.:|     :...:
Mosquito   585 NQIHVHLHGTGSDKFEHYFGSADNGFTINSFPGPSIRSVASGPI--ASTLHAGTAVDIGGIAGAH 647

  Fly   475 HESGPGAVANSRQPSPETTTKIKSA----------AVQQK------------------TVWRPY 510
            |....|..||      :|.|.:.||          :.||:                  :|||||
Mosquito   648 HHQDSGGGAN------DTLTALLSAHHDDPQHSGGSEQQQQQQQDEGRGEESVSGDPSSVWRPY 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
run	NP_523424.2	Runt	107..235	CDD:459963	94/127 (74%)
LOC1273456	XP_061506989.1	None