Protein Alignment run and runx3

DIOPT Version :9

• Sequence 1: NP_001285501.1
• Gene: run / 33059
• FlyBaseID: FBgn0003300
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_002936643.1
• Gene: runx3 / 100485729
• XenbaseID: XB-GENE-487784
• Length: 396
• Species: Xenopus tropicalis
• Alignment Length: 491
• Identity: 153/491 - (31%)
• Similarity: 216/491 - (43%)
• Gaps: 126/491 - (25%)

  Fly    49 IAINPAQSLANTSTHSASSTGSSTPDLSTNNTSSSSNATTSPQNSAKMPSSMTDMFASLHEMLQE 113
            |.::|:.|...|...::...|.    :..||.:.:|:.          |........::.::|.:
 Frog     3 IPVDPSTSRRFTPPSTSFPCGK----MGENNGAINSSG----------PGRTRAEIRTVVDVLAD 53

  Fly   114 YHGELAQTGSPSILCSALPNHWRSNKSLPGAFKVIALDDVPDGTLVSIKCGNDENYCGELRNCTT 178
            :.|||.:|.||:.|||.||:|||.||:||.||||:||.||||||:|::..||||||..||||.:.
 Frog    54 HAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASA 118

  Fly   179 TMKNQVAKFNDLRFVGRSGRGKSFTLTITIATYPVQIASYSKAIKVTVDGPREPR------SKQS 237
            .||||||:|||||||||||||||||||||:.|.|.|:|:|.:|||||||||||||      .:||
 Frog   119 VMKNQVARFNDLRFVGRSGRGKSFTLTITVFTSPTQVATYHRAIKVTVDGPREPRRHRQKLEEQS 183

  Fly   238 YGYPHPGAFNPFMLNPAWLDAAYMTYGYADYFRHQAAAQAAQVHHPALAKSSASSVSPNPNPSVA 302
                     .||                :|.|     :...|...          |.||.||...
 Frog   184 ---------KPF----------------SDRF-----SDLRQTFR----------VQPNSNPRAT 208

  Fly   303 TSSSSAVQPSEYPHPAAAVAAAAGQPAAMMPSPPGAAPATPYAIP-QF--PFNHVAAAAAAKAAT 364
            .:::         :|.::.|....|         |.....|:..| ||  ||:.:.:...::.:.
 Frog   209 LTNT---------NPFSSQAQTQIQ---------GPTDLNPFTDPRQFERPFSALPSLTESRFSD 255

  Fly   365 PHAFHPYNFAAAAGLRA----------------RNAALHHQSEPVHVSPASSRPSSSSPTQQHVL 413
            |...:|...::|....|                .....||...|... |.||: :.|.|.|.:
 Frog   256 PRMHYPSAMSSAFSYTASPSTTGIGGISMTGMPTTTRFHHTYLPPPY-PGSSQ-NQSGPFQTN-- 316

  Fly   414 LKLNTSIETSSIHEQSASDGDSDDEQIDVVKSEFDLDKSLDVAPLRM--RC-DLKAPSAMKPLYH 475
                    .|..|....:  .|...|..:|..|        .:|.||  .| .:...:.:.|...
 Frog   317 --------ASPYHLYYGT--SSGSYQFSMVAGE--------RSPSRMLSSCTSVAGNNLINPNLA 363

  Fly   476 ESGPGAVAN-SRQPSPETTTKIKSAAVQQKTVWRPY 510
            ....|..|: |...||   |.:.::....::|||||
 Frog   364 NQSDGVDADGSHSNSP---TAMTTSGRMDESVWRPY 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
run	NP_001285501.1	Runt	114..235	CDD:279225	86/126 (68%)
runx3	XP_002936643.1	Runt	54..175	CDD:366336	86/120 (72%)
		RunxI	306..396	CDD:369907	24/113 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I3847
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11950
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X738
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.150