Protein Alignment Cyp6v1 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_608403.1
• Gene: Cyp6v1 / 33056
• FlyBaseID: FBgn0031126
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 538
• Identity: 138/538 - (25%)
• Similarity: 248/538 - (46%)
• Gaps: 100/538 - (18%)

  Fly     7 ILLAIVTILTGV---FIWSRRTYVYWQRRRVKFVQPTHLLGNLSRVLRLEESFALQLRRFYFDER 68
            |.|||:|.:.||   ::|   |:.||:||.:.......:||:...:|..|....|||:.  :.::
 Worm     4 IFLAILTSIIGVLSFYLW---TWSYWKRRGIAGPSGYPILGSALEMLSSENPPYLQLKE--WTKQ 63

  Fly    69 FRNEPVVGIYLFHQPALLIRDLQLVRTVLVEDFVSFSNR-FAKCDGRSDKMGALSLFLAKQPEWR 132
            :..  |.||.......|:|.|..||:.|.|:.:.:|..| .....|..:|...::||.::...|:
 Worm    64 YGK--VYGITEGLSRTLVISDPDLVQEVFVKQYDNFFGRKLNPIQGDPNKDKRVNLFSSQGHRWK 126

  Fly   133 EIRTRLAPAFAGAKLKQMFSLMEEIGCDLEWYLKRLTRDLRRGDAERGAIVSIKDVCDLYNTDMI 197
            .:||..:|.|:...|:::.:.:||...:|..::::.|        :.|..:.:.|....:..|:|
 Worm   127 RLRTISSPTFSNNSLRKLKTTVEECAVELLRHIEQHT--------DGGQPIDLLDFYQEFTLDVI 183

  Fly   198 ASIAFGLRSYSLRNTQSEIGSHCQDLFR----PNVRRII-----DLFVIFYL-PKLVPLLRPKLF 252
            ..||.|       .|.|:       :|:    |.||.:.     .||:...| |.:.|:||..:|
 Worm   184 GRIAMG-------QTDSQ-------MFKNPLLPYVRAVFGEPRKGLFLSGSLAPWIGPILRMVMF 234

  Fly   253 TEPH-----AEFLRRVIQLVIEER-------ERGG---DLRNDLIEMLLTLKKEADLQQDKSHFT 302
            :.|:     |..:.|.....:|:|       |:.|   ....|.|::.|      |.:.|.....
 Worm   235 SLPNIVKNPAVHVIRHTSNAVEQRVKLRMADEKAGIDPGEPQDFIDLFL------DAKSDDVELE 293

  Fly   303 HHRDF---------------LAAQAASFEVAGIETCSASMSFALYELAKQPLMQSRLRREI-REA 351
            ::.||               :..|...|.:||.:|.:.|:|::.:.||..|.:|.:|:.|| ||
 Worm   294 NNEDFTKAGVKVTRQLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEIDRE- 357

  Fly   352 FASNPNGRLTYEAVARMEFLDMVVEETLRKYPIVPLLEREC----TPINKKRFYSLRPHAECYTR 412
             .::|  .:|::.::::::::.|::||||.||:..|....|    |.|..   |.:        .
 Worm   358 -CADP--EVTFDQLSKLKYMECVIKETLRMYPLGALANSRCCMRATKIGN---YEI--------D 408

  Fly   413 RGMPVFISNLAIHHDPKYW-PDPDRFDPERFSAANKALQAPMSYMPFGAGPRNCIGMQIGLLQIK 476
            .|..:......:|.|...| .|.:.|.|||:.:.::.......|:|||.|||.||||::..::.|
 Worm   409 EGTNILCDTWTLHSDKSIWGEDAEEFKPERWESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEK 473

  Fly   477 LGLVYFLHQHRVEICDRT 494
            |.|.:.|.::.:|:|::|
 Worm   474 LLLSHILRKYTLEVCNKT 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6v1	NP_608403.1	CYP6-like	70..514	CDD:410679	118/472 (25%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	118/474 (25%)