Protein Alignment Cyp6v1 and cyp3a4

DIOPT Version :10

• Sequence 1: NP_608403.1
• Gene: Cyp6v1 / 33056
• FlyBaseID: FBgn0031126
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_002943949.2
• Gene: cyp3a4 / 100494419
• XenbaseID: XB-GENE-984218
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 537
• Identity: 150/537 - (27%)
• Similarity: 268/537 - (49%)
• Gaps: 77/537 - (14%)

  Fly     5 TNILLAIVTILTGVF-IWSRRTYVYWQRRRVKFVQPTHLLGNLSRVLRLEESFALQLRR--FYFD 66
            |.||||::.:|..:: ||   .|..:::..:....|...:|..           |:.|:  ..||
 Frog    11 TWILLAVLLVLILLYGIW---PYGLFKKMGIPGPTPLPFIGTF-----------LEFRKGMIQFD 61

  Fly    67 -ERFRN-EPVVGIYLFHQPALLIRDLQLVRTVLVED-FVSFSNRFAKCDGRSDKMGALSLFLAKQ 128
             |.|:. ..:.|:|...||.|.|.|..:::|:||:: :.:|:||  :..|.:..:.: ::.:|:.
 Frog    62 IECFKKYGRMWGMYDGRQPVLAIMDPAIIKTILVKECYTNFTNR--RNFGLNGPLES-AITVAED 123

  Fly   129 PEWREIRTRLAPAFAGAKLKQMFSLMEEIGCDLEWYLKRLTRDLRRGDAERGAIVSIKDVCDLYN 193
            .:|:.||:.|:|.|...|||:||.:|::       |...|.::: :...::....:.|||...|:
 Frog   124 EQWKRIRSVLSPTFTSGKLKEMFQIMKD-------YSDILVKNV-QVSVDKDEPCATKDVIGAYS 180

  Fly   194 TDMIASIAFGLRSYSLRNTQSEIGSHCQDLFRPNVRRIIDLFVIFYLPKLVPLLRP-------KL 251
            .|:|.|.:|.:...||:|..:....|.::|.:......:.:|.:.:     |.|||       ..
 Frog   181 MDVITSTSFSVNIDSLQNPSNPFVIHIKNLLKTGFLSPVIIFAVIF-----PFLRPIFEVLNISF 240

  Fly   252 FTEPHAEFLRRVIQLVIEERERGGDL-RNDLIEMLLTLKKEADLQQDKSHFTHHRDF----LAAQ 311
            |.:...:|....:....|:|::|... |.||:::::    ::...:.......|:..    :.||
 Frog   241 FPKDFTQFFMNAVTSFREKRKKGDHSGRVDLLQLMV----DSGTTEGNDSSNQHKALTDAEIMAQ 301

  Fly   312 AASFEVAGIETCSASMSFALYELAKQPLMQSRLRREIREAF---ASNPNGRLTYEAVARMEFLDM 373
            :..|..||.||.|.::|:..|.||..|.:|.:|..|| ::|   .::|    ||:.:.:||:|||
 Frog   302 SLIFIFAGYETTSTALSYLFYNLATHPDVQQKLHEEI-DSFLPDKASP----TYDILMQMEYLDM 361

  Fly   374 VVEETLRKYPIVPLLERECTPINKKRF----YSLRPHAECYTRRGMPVFISNLAIHHDPKYWPDP 434
            |::||||.:|....|||    ::|:..    .|:        .:|....|....:..||:|||:|
 Frog   362 VIQETLRLFPPAGRLER----VSKQNVEINGVSI--------PKGTVAMIPAYVLQRDPEYWPEP 414

  Fly   435 DRFDPERFSAANKALQAPMSYMPFGAGPRNCIGMQIGLLQIKLGLVYFLHQHRVEICDRTVERIQ 499
            :.|.|||||..|:|.|.|.:::|||.|||||||::..||.:|:.:...|....|..|..|:..::
 Frog   415 EEFRPERFSKENRATQTPFTFLPFGDGPRNCIGLRFALLSMKVAIATLLQNFSVRPCAETLIPME 479

  Fly   500 FDAKFALLASEQRIYLK 516
            | :...:|..::.|.||
 Frog   480 F-STIGVLQPKKPIVLK 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6v1	NP_608403.1	CYP6-like	70..514	CDD:410679	130/464 (28%)
cyp3a4	XP_002943949.2	CYP3A	67..495	CDD:410743	131/465 (28%)