Protein Alignment RunxB and runx1

DIOPT Version :9

• Sequence 1: NP_001259745.1
• Gene: RunxB / 33051
• FlyBaseID: FBgn0259162
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_571678.1
• Gene: runx1 / 58126
• ZFINID: ZDB-GENE-000605-1
• Length: 451
• Species: Danio rerio
• Alignment Length: 486
• Identity: 161/486 - (33%)
• Similarity: 206/486 - (42%)
• Gaps: 146/486 - (30%)

  Fly   106 LIERTVDVLLAEHPGELVKTGSPHVVCTTLPTHWRSNKTLPIAFKVLALGEVMDGTIVTIRAGND 170
            :.:|::..:|::||||||:|.||:.:|:.||||||.||||||||||:|||::.|||:||:.||||
Zfish    51 MADRSMVEVLSDHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDIPDGTLVTVMAGND 115

  Fly   171 ENFCGELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTIVISTNPIQIATYTKAIKVTVDGPRE 235
            ||:..||||.||.:|||||:||||||||||||||||||||.:.|||.|:|||.:|||:|||||||
Zfish   116 ENYSAELRNATAAIKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYQRAIKITVDGPRE 180

  Fly   236 PRSKVRHQGFHPFAFGPQRFGPDPLMAGLPFKLPG---FAHHLVGMHSHLHAPDWRAHMALGGRP 297
            ||   ||           |..||..:.      ||   |:..|                    |.
Zfish   181 PR---RH-----------RQKPDEAVK------PGALAFSEQL--------------------RR 205

  Fly   298 AAFTAAPFFGHHAAAFPTASGLRGLSGDSQQHQQQQQQHQLAT-----------------VGAAH 345
            :|...:|   ||..|..|...|......|..|.|.....|:.|                 ..|.|
Zfish   206 SAMRCSP---HHGPAPNTRPTLNTPPFGSPAHSQIPDSRQMQTSPSWSYEQSYPYLGPISTPAVH 267

  Fly   346 STTSPEGSPTTTTTSGTQLSAFVQP-----------------------------PMTSSPPPVTS 381
            .||..  ||..|.....:|:||..|                             ..|.:|.||||
Zfish   268 PTTPI--SPNRTALHCPELTAFTDPRVGLERSFPSLPSLPDGRFSDPRVPYPTGAFTYTPTPVTS 330

  Fly   382 LQHDNNNNNSNNNNSSSHIDAGFESDSISVTGSPRKSLGSPLTHDEEEAEAEAEAEAEAEAEAEE 446
            .                 |..|     :|...||.....:.|      ..|.....::|:|.|.:
Zfish   331 A-----------------IGIG-----MSAMSSPAGRYHTYL------PPAYPAGSSQAQAGAFQ 367

  Fly   447 AEVGGLSRNGGGIQGPLHSESSPGSGGAFTALIQRSGKNPTELFGGFAAAGGNHFAPSGHSFNPA 511
            |.           ..|.|...|..:|....:::...|           ||.|....|.......|
Zfish   368 AS-----------SSPYHLYYSSAAGSYQFSMMPSGG-----------AAAGERSPPRILPCTNA 410

  Fly   512 LAAQLFLQSPLLPQSSQWLYTQLYGSYSDLP 542
            ......|. |.||..|:.: .:..||:|..|
Zfish   411 STGSALLH-PSLPNQSEGV-VEAEGSHSSSP 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RunxB	NP_001259745.1	Runt	118..239	CDD:279225	90/120 (75%)
runx1	NP_571678.1	Runt	63..184	CDD:307137	90/123 (73%)
		Atrophin-1	<160..426	CDD:331285	82/361 (23%)
		RunxI	359..451	CDD:312115	23/105 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	211	1.000	Domainoid score	I2735
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	1	1.000	-	-		mtm6398
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X738
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.010