Protein Alignment RunxB and Runx1

DIOPT Version :9

• Sequence 1: NP_001259745.1
• Gene: RunxB / 33051
• FlyBaseID: FBgn0259162
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: XP_017453542.1
• Gene: Runx1 / 50662
• RGDID: 2283
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 405
• Identity: 141/405 - (34%)
• Similarity: 188/405 - (46%)
• Gaps: 120/405 - (29%)

  Fly   108 ERTVDVLLAEHPGELVKTGSPHVVCTTLPTHWRSNKTLPIAFKVLALGEVMDGTIVTIRAGNDEN 172
            :|::..:||:||||||:|.||:.:|:.||||||.||||||||||:|||:|.|||:||:.||||||
  Rat    62 DRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDEN 126

  Fly   173 FCGELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTIVISTNPIQIATYTKAIKVTVDGPREP- 236
            :..||||.||.||||||:||||||||||||||||||||.:.|||.|:|||.:|||:||||||||
  Rat   127 YSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPR 191

  Fly   237 ----------------------------RSKVRHQGFHP-------------FAFGPQ------- 253
                                        |:.:|....||             .||.||
  Rat   192 RHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQD 256

  Fly   254 --RFGPDP-----------------LMAGLPFKLPGFAHHLVGMHSHLH-----APDWRAHMALG 294
              :..|.|                 :....|.. ||.|..:..:.:.|.     |||..|.
  Rat   257 ARQIQPSPPWSYDQSYQYLGSITSSVHPATPIS-PGRASGMTSLSAELSSRLSTAPDLTAF---- 316

  Fly   295 GRPAAFTAAPFFG----HHAAAF----PTAS----GLRGLSGDSQQHQQQQQQHQLATVGAAHST 347
            |.|..|...|...    |:..||    |..|    |:..:|..|:.|......:.    |::.:.
  Rat   317 GDPRQFPTLPSISDPRMHYPGAFTYSPPVTSGIGIGMSAMSSTSRYHTYLPPPYP----GSSQAQ 377

  Fly   348 TSP--EGSPTTTTTSGTQLSAF-------------VQPPMT-----------SSPPPVTSLQHDN 386
            ..|  .|||:.....||...::             :.||.|           |.|.....::.:.
  Rat   378 AGPFQTGSPSYHLYYGTSAGSYQFSMVGGERSPPRILPPCTNASTGAALLNPSLPSQSDVVETEG 442

  Fly   387 NNNNSNNNNSSSHID 401
            :::||..|...:.::
  Rat   443 SHSNSPTNMPPARLE 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RunxB	NP_001259745.1	Runt	118..239	CDD:279225	92/149 (62%)
Runx1	XP_017453542.1	Runt	68..194	CDD:395684	93/125 (74%)
		RunxI	374..464	CDD:400691	14/84 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	212	1.000	Domainoid score	I2685
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	1	1.000	-	-		mtm8944
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11950
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X738
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.010