Protein Alignment RunxB and lz

DIOPT Version :9

• Sequence 1: NP_001259745.1
• Gene: RunxB / 33051
• FlyBaseID: FBgn0259162
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_511099.2
• Gene: lz / 31883
• FlyBaseID: FBgn0002576
• Length: 826
• Species: Drosophila melanogaster
• Alignment Length: 707
• Identity: 208/707 - (29%)
• Similarity: 288/707 - (40%)
• Gaps: 174/707 - (24%)

  Fly    38 TATTTTTKRRNAESSASSNNNNNNNTSTTNNNNTNNNNNSTTNNNNNNNNNNVKTKPVDTSPYLT 102
            :|:..::......|:.::::.::.:|...:::..:||||:..:|:|:||||.|.
  Fly   213 SASVGSSSPTGGASNGTAHSGHSGHTGGHSSSTASNNNNNGASNSNSNNNNAVH----------- 266

  Fly   103 PENLI--ERTVDVLLAEHPGELVKTGSPHVVCTTLPTHWRSNKTLPIAFKVLALGEVMDGTIVTI 165
             ::|:  ||.|.....|||||||:|.:|:.:|:.||.|||||||||:||||:||.||.|||.|||
  Fly   267 -QDLLWMERLVQKRQQEHPGELVRTSNPYFLCSALPAHWRSNKTLPMAFKVVALAEVGDGTYVTI 330

  Fly   166 RAGNDENFCGELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTIVISTNPIQIATYTKAIKVTV 230
            |||||||.|.||||.|..|||.|||||||||||||||||||||||.::|:|.|:|||.|||||||
  Fly   331 RAGNDENCCAELRNFTTQMKNDVAKFNDLRFVGRSGRGKSFTLTITVATSPPQVATYAKAIKVTV 395

  Fly   231 DGPREPRSKVRHQGF-HPFAFGPQRFGPDPLMAGLPFKLPGFAHHLVGMHSHLHAPDWRAHMALG 294
            |||||||||....|. |..|.|   .|..|.:.|.|....  .|.|..:....     :......
  Fly   396 DGPREPRSKTSPTGGPHYRALG---LGQRPYIDGFPSTKA--LHELESLRRSA-----KVAAVTT 450

  Fly   295 GRPAAFTAAPFFGHHAAA------FPTASG----LRGLSGDSQQHQQQQQQHQLATVGAAHSTTS 349
            ...||.|||......|||      .||..|    ..|::|.             |..|.....:|
  Fly   451 AAAAAATAASAANAVAAAAAAVAVTPTGGGGGVAAGGVAGG-------------AGAGLVQQLSS 502

  Fly   350 PEGSPTTTTTSGTQLSAFVQPPMTSSPPPVTSLQHDNNNNNSNNNNSSS--------------HI 400
            ...||.:|..|..|    |..|   :.|.:.:.:.......:|.::||:              |.
  Fly   503 NYSSPNSTINSDCQ----VYKP---NAPHIQAAEMMGAGEWTNGSSSSAAAYYHSHAHHPHAHHA 560

  Fly   401 DAGFESD---------------SISVTGSPRK-------SLGSPLTH-----DEEEAEAEAEAEA 438
            .|..:..               |:.|.|:...       .:|..:.|     |...:....:..|
  Fly   561 HAHLQHQMALPPPPPPPAAAPVSVGVGGNGATMGMGMGVGVGMGMNHYGGGYDSANSLEAGQYAA 625

  Fly   439 EAEAEAEEAEVGGLSRN-------GGGIQGPLHSESSPGSGGAFTALIQRSGKNPTELFGGFAAA 496
            ...|...|....|.:.:       |||..|          ||:       :.|:..:..|.:..|
  Fly   626 HLPAVLPEMHGHGFATDPYQTAGYGGGNTG----------GGS-------ASKSELDYGGSYNQA 673

  Fly   497 GGNHFAPSGHSFNPALAAQLF-------LQSP------LLPQ-----SSQWLYTQLYGSYSDLPW 543
            ..|.:  ..:.:...||...:       .|.|      |.||     :...::..|:.|.....:
  Fly   674 WSNGY--QNYQYGSCLATAQYGPQAAPPPQPPPPPPVVLCPQLYSTVNQNQIHLHLHSSEKLEQY 736

  Fly   544 LRNAAAAAAANIN--PGQENSGIPPLGSNPDHDGVNLIKRCVTLITHNPPDAENANPNASPPVSS 606
            |..|.:|....|.  .|...|.| .:|.:..|..|           |:....:......
  Fly   737 LGTATSADHLTIGSLTGSSRSSI-EIGQDQYHQQV-----------HHAQQQQQQQQQQ------ 783

  Fly   607 TRRSPSPVETIDLDDVSTTSRSASGSSGHGGGVGGGGAVGPIRTRTPKPSADVWRPY 663
                         ..|....:....|:|..||.|.|| |...|.......:.|||||
  Fly   784 -------------QQVHHPQQQQVESAGEVGGSGAGG-VESAREEDVGDLSQVWRPY 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RunxB	NP_001259745.1	Runt	118..239	CDD:279225	93/120 (78%)
lz	NP_511099.2	Runt	283..404	CDD:279225	93/120 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	132	1.000	Domainoid score	I3175
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D109070at6656
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	1	1.000	-	-		otm14562
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X738
	7	7.020