Protein Alignment RunxB and Runx3

DIOPT Version :9

• Sequence 1: NP_001259745.1
• Gene: RunxB / 33051
• FlyBaseID: FBgn0259162
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_569109.1
• Gene: Runx3 / 156726
• RGDID: 620082
• Length: 409
• Species: Rattus norvegicus
• Alignment Length: 394
• Identity: 147/394 - (37%)
• Similarity: 190/394 - (48%)
• Gaps: 71/394 - (18%)

  Fly   103 PENLIERTVDVLLAEHPGELVKTGSPHVVCTTLPTHWRSNKTLPIAFKVLALGEVMDGTIVTIRA 167
            ||  :...||| ||:|.||||:|.||:.:|:.||:|||.|||||:||||:|||:|.|||:||:.|
  Rat    51 PE--VRSMVDV-LADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMA 112

  Fly   168 GNDENFCGELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTIVISTNPIQIATYTKAIKVTVDG 232
            |||||:..||||.:||||||||:||||||||||||||||||||.:.|||.|:|||.:||||||||
  Rat   113 GNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDG 177

  Fly   233 PREP---RSKVRHQGFHPFAFGPQRFGPDPLMAGLPFKLPGFAHHLVGMHSHLHAPDWRAHMALG 294
            ||||   |.|:..|   ..|| |.||| |..|...|                 ..|..|..::..
  Rat   178 PREPRRHRQKIEDQ---TKAF-PDRFG-DLRMRVTP-----------------STPSPRGSLSTT 220

  Fly   295 GRPAAFTAAPFFG-----------HHAAAFPTASGLRGLSGDSQQHQQQQQQHQLATVGAAHSTT 348
            ...::....|..|           ....:|||...|      ::....:.:.|....:.||.
  Rat   221 SHFSSQAQTPIQGSSDLNPFSDPRQFDRSFPTLQSL------TESRFPEGRMHYPGAMSAAF--- 276

  Fly   349 SPEGSPTTTTTSGTQLSAFVQPPMTSS--------PPPVTSLQHDNNNNNSNNNNSSSHIDAGFE 405
                 |.:.|.|||.|.......|.:|        |||..... .:.:.....|.:..|:..|..
  Rat   277 -----PYSATPSGTSLGGLSVAGMPASSRFHHTYLPPPYPGAP-QSQSGPFQANPAPYHLFYGTS 335

  Fly   406 SD----SISVTGSPRKSLGSPLTHDEEEAEAEAEAEAEAEAEAEEAEVGGLSRNGGGIQGPLHSE 466
            |.    |::..|...:|....||    .....|...|.........:..|:..:|.....|. :.
  Rat   336 SGSYQFSMAAAGGGERSPTRMLT----SCPTGASVSAGNLMNPSLGQADGVEADGSHSNSPT-AL 395

  Fly   467 SSPG 470
            |:||
  Rat   396 STPG 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RunxB	NP_001259745.1	Runt	118..239	CDD:279225	90/123 (73%)
Runx3	NP_569109.1	Runt	63..184	CDD:279225	89/120 (74%)
		RunxI	314..409	CDD:285676	17/92 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	212	1.000	Domainoid score	I2685
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	212	1.000	Inparanoid score	I3567
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	1	1.000	-	-		mtm8944
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11950
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X738
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060