Protein Alignment RunxB and runx3

DIOPT Version :9

• Sequence 1: NP_001259745.1
• Gene: RunxB / 33051
• FlyBaseID: FBgn0259162
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: XP_002936643.1
• Gene: runx3 / 100485729
• XenbaseID: XB-GENE-487784
• Length: 396
• Species: Xenopus tropicalis
• Alignment Length: 362
• Identity: 145/362 - (40%)
• Similarity: 178/362 - (49%)
• Gaps: 107/362 - (29%)

  Fly   109 RTVDVLLAEHPGELVKTGSPHVVCTTLPTHWRSNKTLPIAFKVLALGEVMDGTIVTIRAGNDENF 173
            |||..:||:|.||||:|.||:.:|:.||:|||.|||||:||||:|||:|.|||:||:.||||||:
 Frog    45 RTVVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENY 109

  Fly   174 CGELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTIVISTNPIQIATYTKAIKVTVDGPREPRS 238
            ..||||.:||||||||:||||||||||||||||||||.:.|:|.|:|||.:|||||||||||||
 Frog   110 SAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTSPTQVATYHRAIKVTVDGPREPR- 173

  Fly   239 KVRH-------------------QGF---------------HPFAF-------GPQRFGP--DPL 260
              ||                   |.|               :||:.       ||....|  ||.
 Frog   174 --RHRQKLEEQSKPFSDRFSDLRQTFRVQPNSNPRATLTNTNPFSSQAQTQIQGPTDLNPFTDPR 236

  Fly   261 MAGLPFK-LPGFAHHLVGMHSHLHAPDWRAHMALGGRPAAFTAAPFFGHHAAAFPTASGLRGLSG 324
            ....||. ||...      .|....|  |.|.     |:|.::|  |.:.|:  |:.:|:.|:
 Frog   237 QFERPFSALPSLT------ESRFSDP--RMHY-----PSAMSSA--FSYTAS--PSTTGIGGI-- 282

  Fly   325 DSQQHQQQQQQHQLATVGAAHSTTSPEGSPTTTTTSGTQLSAFVQPPMTSSPPPVTSLQHDNNNN 389
                                    |..|.||||....|.|           |||... ...|.:.
 Frog   283 ------------------------SMTGMPTTTRFHHTYL-----------PPPYPG-SSQNQSG 311

  Fly   390 NSNNNNSSSHIDAGFESDSIS---VTG--SPRKSLGS 421
            ....|.|..|:..|..|.|..   |.|  ||.:.|.|
 Frog   312 PFQTNASPYHLYYGTSSGSYQFSMVAGERSPSRMLSS 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RunxB	NP_001259745.1	Runt	118..239	CDD:279225	89/120 (74%)
runx3	XP_002936643.1	Runt	54..175	CDD:366336	89/123 (72%)
		RunxI	306..396	CDD:369907	13/43 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	213	1.000	Domainoid score	I2697
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I3847
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	1	1.000	-	-		mtm9362
Panther	1	1.100	-	-	O	PTHR11950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X738
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060