DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG1812 and AFR

DIOPT Version :9

Sequence 1:NP_608397.1 Gene:CG1812 / 33049 FlyBaseID:FBgn0031119 Length:616 Species:Drosophila melanogaster
Sequence 2:NP_565572.1 Gene:AFR / 816990 AraportID:AT2G24540 Length:372 Species:Arabidopsis thaliana


Alignment Length:396 Identity:86/396 - (21%)
Similarity:137/396 - (34%) Gaps:120/396 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   289 KDQSLPQG-PTNMRGMELCLLKIG----------GFEWN-GLTNVIMCFSPKKMN---------- 331
            |.|.|..| |.::  .|||||::.          ...|| .:||....||.:.::          
plant    24 KSQPLISGLPNDI--AELCLLRLPYPYHALYRSVSSSWNKTITNPRFLFSKQSLSISSPYLFVFA 86

  Fly   332 -------------------WYELTAI---------PHIDQCNFGTAVLNNKLFIVGGAYDVFLKE 368
                               |:.|..:         ||...|  .:.....|||::||. ||....
plant    87 FNKSTARIQWQSLDLASGRWFVLPPMPNSFTKISSPHALSC--ASMPRQGKLFVLGGG-DVNRSA 148

  Fly   369 YIHPFGFCYCPLRNTWMTIAPIQQDRCRF-SLNAVGTQHLYAVGGILDDDNEEALRMISNVERYD 432
            .:      |..|.|.|..|:|:...|..| |.|..|  .:.||||.:..:.|..    :.||.||
plant   149 VV------YTALTNRWSCISPMMSPRTYFVSGNVNG--KIMAVGGSVGGNGEAT----TEVESYD 201

  Fly   433 IAKNVWTYMPSLQENRSQHAGVVVGDKLYISGGVHLANILASMW-----------VFDTKTEVWQ 486
            ...:.||.:..|....:::...|:|.::.::.|          |           |:|:....|:
plant   202 PDNDTWTVVKKLPMVLAKYDSAVIGKEMCVTEG----------WAWPFMFPPMGQVYDSDEGTWR 256

  Fly   487 ELASMPTPCCDHVLVAVDNRIYACGGWHESLTEWRVLVEH----IYAYDIETNTWSVET------ 541
            |::.........|.|.:.:|::             |:.||    :..|..:.:||...:      
plant   257 EMSGGMKEGWTGVSVVIRDRLF-------------VISEHGDFPMKVYCSDDDTWRYVSGEKLQG 308

  Fly   542 -KIPAPKFYTGVTAMGRTIFFVGGLDSTESIDRASAETMAYDLDTKEWWHEKDSWDSPNDVWEST 605
             |:..|...||  |..|......|::..|.  |.| |....|...:  |....|..|......::
plant   309 EKMRRPFAVTG--ADDRVFVVASGINVAEG--RVS-EGQNGDFSVE--WRMVSSPKSSIQFSPAS 366

  Fly   606 CVAIYV 611
            |..:||
plant   367 CHVLYV 372

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1812NP_608397.1 BTB 38..142 CDD:279045
PHA03098 46..588 CDD:222983 80/371 (22%)
BACK 151..249 CDD:285009
KELCH repeat 344..390 CDD:276965 13/45 (29%)
KELCH repeat 394..444 CDD:276965 16/50 (32%)
Kelch 406..458 CDD:128874 13/51 (25%)
Kelch_1 448..492 CDD:279660 8/54 (15%)
KELCH repeat 448..492 CDD:276965 8/54 (15%)
Kelch_1 494..539 CDD:279660 9/48 (19%)
KELCH repeat 495..539 CDD:276965 9/47 (19%)
AFRNP_565572.1 F-box 27..72 CDD:279040 13/46 (28%)
Kelch_1 167..214 CDD:279660 16/52 (31%)
KELCH repeat 168..214 CDD:276965 16/51 (31%)
KELCH repeat 217..259 CDD:276965 8/51 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1072
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 57 1.000 Inparanoid score I2576
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X9
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.860

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