DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG1812 and Klhdc8b

DIOPT Version :9

Sequence 1:NP_608397.1 Gene:CG1812 / 33049 FlyBaseID:FBgn0031119 Length:616 Species:Drosophila melanogaster
Sequence 2:NP_001346357.1 Gene:Klhdc8b / 78267 MGIID:1925517 Length:354 Species:Mus musculus


Alignment Length:243 Identity:61/243 - (25%)
Similarity:101/243 - (41%) Gaps:43/243 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   339 PHIDQCN-FGT-AVLNNKLFIVGGAYDVFLKEYIHPFGFCYCPL---------RNTWMTIAPIQQ 392
            |.:..|. :|| |..:..|.::||.            |....||         .:||:.:||:..
Mouse    15 PPMPTCRVYGTVAHQDGHLLVLGGC------------GRAGLPLDTAETLDMGSHTWLALAPLPT 67

  Fly   393 DRCRFSLNAVGTQHLYAVGGILDDDNEEALRMISNVERYDIAKNVWTYMPSLQENRSQHAGVVVG 457
            .|...:...:|.|.| .|||:     :|....::.||.:...:..|....:|.:.....|.|...
Mouse    68 ARAGAAAVVLGKQVL-VVGGV-----DEVQSPVAAVEAFLADEGRWERRATLPQAAMGVATVERD 126

  Fly   458 DKLYISGGV-----HLANILASMWVFDTKTEVWQELASMPTPCCDHVLVAVDNRIYACGGWHESL 517
            ..:|..||:     ..|.:|    |::.:.:.|..|.||||||.........|:||..||     
Mouse   127 GMVYALGGMGPDTAPQAQVL----VYEPRRDCWLSLPSMPTPCYGASTFLHGNKIYVLGG----- 182

  Fly   518 TEWRVLVEHIYAYDIETNTWSVETKIPAPKFYTGVTAMGRTIFFVGGL 565
            .:.::.|....|:|:||.||:....:|:.:.:.|......::|.:|||
Mouse   183 RQGKLPVTAFEAFDLETRTWTRHPSLPSRRAFAGCAMAEGSVFSLGGL 230

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1812NP_608397.1 BTB 38..142 CDD:279045
PHA03098 46..588 CDD:222983 61/243 (25%)
BACK 151..249 CDD:285009
KELCH repeat 344..390 CDD:276965 13/56 (23%)
KELCH repeat 394..444 CDD:276965 11/49 (22%)
Kelch 406..458 CDD:128874 11/51 (22%)
Kelch_1 448..492 CDD:279660 11/48 (23%)
KELCH repeat 448..492 CDD:276965 11/48 (23%)
Kelch_1 494..539 CDD:279660 14/44 (32%)
KELCH repeat 495..539 CDD:276965 13/43 (30%)
Klhdc8bNP_001346357.1 Kelch 1 1..31 5/15 (33%)
PHA03098 <7..210 CDD:222983 55/221 (25%)
KELCH repeat 21..66 CDD:276965 13/56 (23%)
Kelch 2 32..79 11/58 (19%)
KELCH repeat 69..113 CDD:276965 11/49 (22%)
Kelch 3 81..127 11/51 (22%)
KELCH repeat 117..162 CDD:276965 11/48 (23%)
Kelch 4 128..175 14/50 (28%)
PHA03098 <129..336 CDD:222983 32/111 (29%)
KELCH repeat 165..210 CDD:276965 13/49 (27%)
Kelch 5 176..222 13/50 (26%)
KELCH repeat 212..262 CDD:276965 5/19 (26%)
Kelch 6 224..281 4/7 (57%)
KELCH repeat 271..317 CDD:276965
Kelch 7 282..329
Kelch 8 331..354
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1072
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X9
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.900

Return to query results.
Submit another query.