Protein Alignment CG1812 and klhl32

DIOPT Version :10

• Sequence 1: NP_608397.1
• Gene: CG1812 / 33049
• FlyBaseID: FBgn0031119
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: XP_012818485.1
• Gene: klhl32 / 549611
• XenbaseID: XB-GENE-5858956
• Length: 657
• Species: Xenopus tropicalis
• Alignment Length: 563
• Identity: 161/563 - (28%)
• Similarity: 262/563 - (46%)
• Gaps: 62/563 - (11%)

  Fly    31 EETLLRGLNKLRNEEKLTDVTLIVEEHRFKAHRVVLAASSDYFCAMFADCAMIESRKDEINLYGI 95
            ::.:|..||:.||:..|.|:||:.||.:|.||:.||||.||||.|||:.| |:||..||:||:|:
 Frog    62 KDAVLSALNQQRNDGILCDITLVAEEQKFHAHKAVLAACSDYFRAMFSLC-MVESEADEVNLHGV 125

  Fly    96 KARAMGSIIDYIYTSMLELNYDNIEEILAAATHVQVREVIDRCTIFLGAKIEMENCLAIAGMADI 160
            .:..:...:|:.||..:.|....|:::|||.:|:|:.|:::.|:.:|..::...|.|.:..:||:
 Frog   126 TSLGLKQALDFAYTGQILLEPGAIQDVLAAGSHLQLLELLNLCSQYLIQELNSFNYLDLYKLADL 190

  Fly   161 YGIMDLSERAYRYMCAHFEEFATT--SDFKEMKVDQLRFILSSNYPIDVAEQDLVRLVCSFAIEQ 223
            :.:..|......::..|..|....  .:...:....||.:|.|:....::|:.:.:|...: :|.
 Frog   191 FNLTLLETAVVEFLVKHLSELLKNHPEEVLALPFRLLREVLKSDQLTSMSEEQIWQLAVRW-LEH 254

  Fly   224 QLNESALGDLLRLIKWQHISYKSVDELRNMNCSLDKGKQLPLPTSYYNRIKQEHMGHLLNGVVSL 288
            ......:.:||:.:::   .....:.|..:..|....:.....|:..|...:.|
 Frog   255 NCRYQYMDELLQYVRF---GLMDTNTLHTVALSHPLIQSSETATALINEALEYH----------- 305

  Fly   289 KDQSLPQGP------TNMRGMELCLLKIGGFEWNGLTNV--IMCFSPKKM---------NWYELT 336
              ||:...|      |..|.....|..:|| :...:..|  :..|:|...         ||.|||
 Frog   306 --QSIYAQPVWQTIRTEPRFQSNTLYIVGG-KKREICKVRELRYFNPIDQENVHIAGIANWSELT 367

  Fly   337 AIPHIDQCNFGTAVLNNKLFIVGGAYDVFLKEYIHPFG-------FC-YCPLRNTWMTIAPIQQD 393
            .:| :.:.:...|::.|.||..||       |..|..|       .| |.|..|:|:.|||::..
 Frog   368 PMP-VGRSHHCVAIMGNFLFAAGG-------EVEHASGRTCAVRTACRYDPRSNSWIEIAPMKNC 424

  Fly   394 RCRFSLNAVGTQHLYAVGGILDDDNEEALRMISNVERYDIAKNVWTYMPSLQENRSQHAGVVVGD 458
            |..|.|.||| ..||||||     ..|..:::.:||||...||.||:..|...:.|.|||.|...
 Frog   425 REHFVLGAVG-DLLYAVGG-----RNELRQVLPSVERYCPKKNKWTFAQSFDRSLSCHAGCVADG 483

  Fly   459 KLYISGGV-HLANILASMWVFDTKTEVWQELASMPTPCCDHVLVAVDNRIYACGGWHESLTEWRV 522
            .|:||||| :.|.....:.|:|.....|...:.|......|.:.||..::|..||........|:
 Frog   484 LLWISGGVTNTAQYQNRLMVYDPSQNKWISRSPMLQRRVYHAMAAVQRKLYVLGGNDLDYNNDRI 548

  Fly   523 LVEHIYAYDIETNTWS-VETKIPAPKFYTGVTAMGRTIFFVGG 564
            ||.||.:|:|:|:.|: ....:...:..:||......|:.|||
 Frog   549 LVRHIDSYNIDTDQWTRCNFNLLTGQNESGVAVYNGRIYLVGG 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1812	NP_608397.1	BTB_POZ	33..151	CDD:453885	47/117 (40%)
		PHA03098	46..588	CDD:222983	156/548 (28%)
		KELCH repeat	344..390	CDD:276965	16/53 (30%)
		KELCH repeat	394..444	CDD:276965	21/49 (43%)
		KELCH repeat	448..492	CDD:276965	15/44 (34%)
		KELCH repeat	495..539	CDD:276965	15/44 (34%)
klhl32	XP_012818485.1	BTB_POZ_KLHL32	51..183	CDD:349570	48/121 (40%)
		PHA03098	74..564	CDD:222983	150/522 (29%)
		BACK_KLHL32_BKLHD5	176..273	CDD:350546	16/100 (16%)
		KELCH repeat	373..421	CDD:276965	16/54 (30%)
		KELCH repeat	425..470	CDD:276965	22/50 (44%)
		KELCH repeat	473..519	CDD:276965	16/45 (36%)
		KELCH repeat	521..571	CDD:276965	15/49 (31%)