Protein Alignment CG1812 and klhl13

DIOPT Version :10

• Sequence 1: NP_608397.1
• Gene: CG1812 / 33049
• FlyBaseID: FBgn0031119
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: XP_005165329.1
• Gene: klhl13 / 323951
• ZFINID: ZDB-GENE-030131-2671
• Length: 682
• Species: Danio rerio
• Alignment Length: 600
• Identity: 174/600 - (28%)
• Similarity: 274/600 - (45%)
• Gaps: 81/600 - (13%)

  Fly    34 LLRGLNKLRNEEKLTDVTLIV--EEHRFKAHRVVLAASSDYFCAMFADCAMIESRKDEINLYGIK 96
            :|:|.::||.|..|.||||:.  .:..|..||.::|:|||||.|||.. .|.|.....|.|:|:.
Zfish   103 VLQGFDQLRIEGLLCDVTLVAGDGDEAFPVHRAMMASSSDYFKAMFTG-GMKEQDLMCIKLHGVN 166

  Fly    97 ARAMGSIIDYIYTSMLELNYDNIEEILAAATHVQVREVIDRCTIFLGAKIEMENCLAIAGMADIY 161
            ...:..|||:|||:.|.||.:|:::.|.||:.:|:..|:|.|.:||.:.:.::||:.:..:|:.|
Zfish   167 RIGLKKIIDFIYTAKLSLNMENLQDTLEAASFLQILPVLDFCKVFLISGVSLDNCVEVGRIANTY 231

  Fly   162 GIMDLSERAYRYMCAHFEEFATTSDFKEMKVDQLRFILSSNYPIDVAEQDLVRLVCSFAIEQQLN 226
            .:.::.:....::..:|.....|.:|.::..::|.|:||||.....:|.||.:..|.:...::..
Zfish   232 NLTEVDKYVNNFILKNFPSLLGTGEFVKLPFERLAFVLSSNSLKHCSELDLFKSACRWLRYEEGR 296

  Fly   227 ESALGDLLRLIKWQHIS-------YKSVDELRNMNCSLDKGKQLPLPTSYYNRIKQEHMGHLLNG 284
            ......|:|.|::..:|       .::||.:|..|..::    |.|..|.|     :.|.::
Zfish   297 MEYAAKLMRNIRFPLMSPTELINHVQTVDFMRTDNTCVN----LLLEASNY-----QMMPYM--- 349

  Fly   285 VVSLKDQSLPQGP-TNMRGMELCLLKIGGFEWNGL--TNVIMCFSPKKMNWYELTAIPHIDQCNF 346
                  |.:.|.. |.:|.....|:.:||.....|  :..:..|..|...|   .|:..:|...:
Zfish   350 ------QPVMQSERTAIRSDNTHLVTLGGVLRQQLVVSKELRLFDEKAHEW---KALAPMDAPRY 405

  Fly   347 --GTAVLNNKLFIVGGA--YDVFLKEYIHPFGFCYCPLRNTWMTIAPIQQDRCRFSLNAVGTQHL 407
              |.||:.|.|::|||.  ||...|..:... |.|.|..|.|:.:|.:.:.|..|.|:|: ..:|
Zfish   406 QHGIAVIGNFLYVVGGQSNYDTKGKTAVDTV-FRYDPRYNKWIQVACLNEKRTFFHLSAL-KGYL 468

  Fly   408 YAVGGILDDDNEEALRMISNVERYDIAKNVWTYMPSLQENRSQHAGVVVGDKLYISGGVHLANIL 472
            |||||      ..|...::.||.|:...|.|||:..:.|....|||.|.|..:|||||:......
Zfish   469 YAVGG------RNAAGELATVECYNPRTNEWTYVAKMSEPHYGHAGTVYGGYMYISGGITHDTFQ 527

  Fly   473 ASMWVFDTKTEVWQELASMPTPCCDHVLVAVDNRIYACGGWHESLTEWRVLVEHIYAYDIETNTW 537
            ..:..||...:.|.:.|.|.|....|.:..|.:|:|..||.|...|.         .||   :..
Zfish   528 KELMCFDPDADKWTQKAPMTTVRGLHCMCTVGDRLYVIGGNHFRGTS---------DYD---DVL 580

  Fly   538 SVETKIPAPKFYTGVTAMGR------------TIFFVGGLDSTESIDRASAE-TMAYDLDTKEWW 589
            |.|...||...:|.:.||.|            .|:.|||....   :|...| ...||
Zfish   581 SCEYYSPALDLWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWN---NRCMVEIVQKYD------- 635

  Fly   590 HEKDSWDSPNDVWES 604
            .|||.|....|:.||
Zfish   636 PEKDEWHKVFDLPES 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1812	NP_608397.1	BTB_POZ	33..151	CDD:453885	46/118 (39%)
		PHA03098	46..588	CDD:222983	162/570 (28%)
		KELCH repeat	344..390	CDD:276965	17/49 (35%)
		KELCH repeat	394..444	CDD:276965	18/49 (37%)
		KELCH repeat	448..492	CDD:276965	14/43 (33%)
		KELCH repeat	495..539	CDD:276965	10/43 (23%)
klhl13	XP_005165329.1	BTB_POZ_KLHL9_13	94..221	CDD:349548	46/118 (39%)
		PHA03098	117..660	CDD:222983	167/585 (29%)
		KELCH repeat	404..452	CDD:276965	17/48 (35%)
		KELCH repeat	456..500	CDD:276965	18/50 (36%)
		KELCH repeat	503..548	CDD:276965	15/44 (34%)
		KELCH repeat	550..599	CDD:276965	16/60 (27%)
		KELCH repeat	602..649	CDD:276965	13/56 (23%)