Protein Alignment CG1812 and CG17754

DIOPT Version :10

• Sequence 1: NP_608397.1
• Gene: CG1812 / 33049
• FlyBaseID: FBgn0031119
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: NP_572549.2
• Gene: CG17754 / 31873
• FlyBaseID: FBgn0030114
• Length: 654
• Species: Drosophila melanogaster
• Alignment Length: 606
• Identity: 157/606 - (25%)
• Similarity: 266/606 - (43%)
• Gaps: 78/606 - (12%)

  Fly    32 ETLLRGLNKLRNEEKLTDVTLI--VEEHRFKAHRVVLAASSDYFCAMFADCAMIESRKDEINLYG 94
            :.:|:.:....:.::|.||.||  ::..|..|||:||:|||.||.|||.. ::.|:::.|:.|..
  Fly    59 DNILKRMQLYVDSQQLCDVVLIAGIDGKRVPAHRLVLSASSAYFSAMFTG-SLRETKEQEVTLGE 122

  Fly    95 IKARAMGSIIDYIYTSMLELNYDNIEEILAAATHVQVREVIDRCTIFLGAKIEMENCLAIAGMAD 159
            :...|:..::.|.||..:|:..|.:|.:||.|..:|:..|:..|..||..::...|||..|..|:
  Fly   123 VHGDALHLLVQYCYTGFIEMREDTVETLLATACLLQLNAVVTACCNFLARQLHPSNCLGFAFFAE 187

  Fly   160 IYGIMDLSERAYRYMCAHFEEFATTSDFKEMKVDQLRFILSS---NYPIDVAEQDLVRLVCSFA- 220
            ......|...|..|.|.:|.:.....:|.::..|||..:|||   |.|   :|||:...:.|:.
  Fly   188 QQSCTTLLRLAQAYTCQYFMQVCQNQEFFQLNADQLGKLLSSDDLNVP---SEQDVFHSLMSWVR 249

  Fly   221 IEQQLNESALGDLLRLIKWQHISYKSV-DELRNMNCSLDKGKQLPLPTSYYNRIKQEHMGHLLNG 284
            .:....|..:.:||.|::...:....: |.:.|: |:.::.:||         :.:....||:..
  Fly   250 HDSAAREQHIPELLALVRLPLLQPAFIMDHVENV-CNANECQQL---------VMEAFKWHLMPE 304

  Fly   285 VVS--LKDQSLPQGPTNMRGMELCLLKIGGFEWNGLTNVIMCFSPKKMNWYELTAIPHID--QCN 345
            ..|  ..:::.|:..|..|     ||.:||.:.:.....|..:.|:...|   |...|:.  :..
  Fly   305 RRSRIATERTTPRKSTVGR-----LLAVGGMDAHKGAISIESYCPRLDKW---TPWKHMTGRRLQ 361

  Fly   346 FGTAVLNNKLFIVGGAYDVFLKEYIHPFGFCYCPLRNTWMTIAPIQQDRCRFSLNAVGT-QH--- 406
            ||.||:.:||.:|||...:.....:.....      || |..||         |||:.| :|
  Fly   362 FGAAVMEDKLILVGGRDGLKTLNTVESLDL------NT-MAWAP---------LNAMATPRHGLG 410

  Fly   407 -------LYAVGGILDDDNEEALRMISNVERYDIAKNVWTYMPSLQENRSQHAGVVVGDKLYISG 464
                   ||||||      .:....::.|||:|.....|:|:..:...||.....|:|.:||..|
  Fly   411 VAVLEGPLYAVGG------HDGWSYLNTVERWDPIARTWSYVAPMSSMRSTAGVAVLGGRLYAVG 469

  Fly   465 GVHLANILASMWVFDTKTEVWQELASMPTPCCDHVLVAVDNRIYACGGWHESLTEWRVL--VEHI 527
            |...:....|:..:|..|..|..||.|........:...:..:||.|| |:......::  .|.:
  Fly   470 GRDGSVCHRSIECYDPHTNKWSLLAPMNRRRGGVGVTVANGFLYALGG-HDCPASNPMVCRTETV 533

  Fly   528 YAYDIETNTWSVETKIPAPKFYTGVTAMGRTIFFVGGLDSTESIDRASAETMAYDLDTKEWWHEK 592
            ..||..|:||::...:...:...|...:|..:..|||.|...::  .|.|  .|| ..:..|:|.
  Fly   534 ERYDPATDTWTLICSLALGRDAIGCALLGDRLIVVGGYDGNHAL--KSVE--EYD-PVRNGWNEL 593

  Fly   593 DSWDSPNDVWESTCVAIYVPN 613
                :|.....:....:.:||
  Fly   594 ----APMAFARAGACVVAIPN 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1812	NP_608397.1	BTB_POZ	33..151	CDD:453885	38/119 (32%)
		PHA03098	46..588	CDD:222983	151/565 (27%)
		KELCH repeat	344..390	CDD:276965	13/45 (29%)
		KELCH repeat	394..444	CDD:276965	17/60 (28%)
		KELCH repeat	448..492	CDD:276965	14/43 (33%)
		KELCH repeat	495..539	CDD:276965	11/45 (24%)
CG17754	NP_572549.2	PHA03098	71..591	CDD:222983	151/569 (27%)
		KELCH repeat	359..402	CDD:276965	16/58 (28%)
		KELCH repeat	406..449	CDD:276965	13/48 (27%)
		KELCH repeat	453..497	CDD:276965	14/43 (33%)
		KELCH repeat	500..549	CDD:276965	11/49 (22%)
		KELCH repeat	553..596	CDD:276965	12/51 (24%)