DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1812 and KLHDC8B

DIOPT Version :9

Sequence 1:NP_608397.1 Gene:CG1812 / 33049 FlyBaseID:FBgn0031119 Length:616 Species:Drosophila melanogaster
Sequence 2:XP_006713078.1 Gene:KLHDC8B / 200942 HGNCID:28557 Length:371 Species:Homo sapiens


Alignment Length:255 Identity:60/255 - (23%)
Similarity:102/255 - (40%) Gaps:50/255 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   339 PHIDQCN-FGT-AVLNNKLFIVGGAYDVFLKEYIHPFGFCYCPL---------RNTWMTIAPIQQ 392
            |.:..|. :|| |..:..|.::||.            |....||         .:||:.:||:..
Human    15 PPMPTCRVYGTVAHQDGHLLVLGGC------------GRAGLPLDTAETLDMASHTWLALAPLPT 67

  Fly   393 DRCRFSLNAVGTQHLYAVGGILDDDNEEALRMISNVERYDIAKNVWTYMPSLQENRSQHAGVVVG 457
            .|...:...:|.|.| .|||:     :|....::.||.:.:.:..|....:|.:.....|.|..|
Human    68 ARAGAAAVVLGKQVL-VVGGV-----DEVQSPVAAVEAFLMDEGRWERRATLPQAAMGVATVERG 126

  Fly   458 D----------KLYISGGVHLANI-LASMWVFDTKTEVWQELASMPTPCCDHVLVAVDNRIYACG 511
            :          .:|..||:..... .|.:.|::.:.:.|..|.||||||.........|:||..|
Human   127 EWPPKEGTSDGMVYALGGMGPDTAPQAQVRVYEPRRDCWLSLPSMPTPCYGASTFLHGNKIYVLG 191

  Fly   512 ------GWHESLTEWRVLVEHIYAYDIETNTWSVETKIPAPKFYTGVTAMGRTIFFVGGL 565
                  |..:.    ::.|....|:|:|..||:....:|:.:.:.|......::|.:|||
Human   192 TPIPLTGGRQG----KLPVTAFEAFDLEARTWTRHPSLPSRRAFAGCAMAEGSVFSLGGL 247

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1812NP_608397.1 BTB 38..142 CDD:279045
PHA03098 46..588 CDD:222983 60/255 (24%)
BACK 151..249 CDD:285009
KELCH repeat 344..390 CDD:276965 13/56 (23%)
KELCH repeat 394..444 CDD:276965 11/49 (22%)
Kelch 406..458 CDD:128874 11/51 (22%)
Kelch_1 448..492 CDD:279660 11/54 (20%)
KELCH repeat 448..492 CDD:276965 11/54 (20%)
Kelch_1 494..539 CDD:279660 13/50 (26%)
KELCH repeat 495..539 CDD:276965 12/49 (24%)
KLHDC8BXP_006713078.1 PRK14131 1..321 CDD:237617 60/255 (24%)
Kelch_6 20..69 CDD:290672 14/60 (23%)
KELCH repeat 21..65 CDD:276965 12/55 (22%)
Kelch_1 68..114 CDD:279660 11/51 (22%)
KELCH repeat 69..114 CDD:276965 11/50 (22%)
KELCH repeat 117..173 CDD:276965 12/55 (22%)
Kelch 139..184 CDD:128874 13/44 (30%)
KELCH repeat 175..227 CDD:276965 12/55 (22%)
Kelch 186..239 CDD:128874 12/56 (21%)
Kelch_1 228..279 CDD:279660 5/20 (25%)
KELCH repeat 229..279 CDD:276965 5/19 (26%)
Kelch_6 288..336 CDD:290672
KELCH repeat 288..334 CDD:276965
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1072
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X9
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.900

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