Protein Alignment CG1812 and kel-20

DIOPT Version :10

• Sequence 1: NP_608397.1
• Gene: CG1812 / 33049
• FlyBaseID: FBgn0031119
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: NP_491322.2
• Gene: kel-20 / 172012
• WormBaseID: WBGene00020030
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 592
• Identity: 165/592 - (27%)
• Similarity: 259/592 - (43%)
• Gaps: 97/592 - (16%)

  Fly    33 TLLRGLNKLRNEEKLTDVTLIVEEHRFKAHRVVLAASSDYFCAMF----ADCAMIESRKDEINLY 93
            ::|:.|..|:|.:.|.|||||....|..||||||:|.|.||.:||    |:|.|     .|||:.
 Worm    41 SVLQQLGGLKNRDVLCDVTLICGWKRINAHRVVLSACSPYFLSMFTSQMAECYM-----REINME 100

  Fly    94 GIKARAMGSIIDYIYTSMLELNYDNIEEILAAATHVQVREVIDRCTIFLGAKIEMENCLAIAGMA 158
            .|:...:.::|::.||..:.::..|:::||.||..:|:.||...|..:|..:::..|||.|...|
 Worm   101 EIEPPTLEALIEFCYTGAIAIDDSNVQDILPAACLLQIHEVQTACCDYLKKQLDPSNCLGIRAFA 165

  Fly   159 DIYGIMDLSERAYRYMCAHFEEFATTSDFKEMKVDQLRFILSSNYPIDVAEQDLVRLVCSFAIEQ 223
            |.:...:|...|..:...:|.......:|:.:.|:.|..|:.|: .::.|.::||.......:..
 Worm   166 DTHSCKELLSSADEFALKNFSRVIGKEEFQMLTVESLTTIIKSD-KLNAASEELVFSAVIQWVRH 229

  Fly   224 QLN--ESALGDLLR--------------------LIKWQHISYKSVDELRNMNCSLDKGKQLPLP 266
            .::  ::.|..||.                    |:|....|...|||.:|         .|.||
 Worm   230 DISKRKTHLSMLLSHVRLPLCTPKFLVSVVSEEILVKSDPASRDLVDEAKN---------YLLLP 285

  Fly   267 TSYYNRIKQEHMGHLLNGVVSLKDQSLPQGPTN-----MRGMELCLLKIGGFEWNGLTNVIMCFS 326
                  :::.:|                |||..     ::|.|: |..:||:........|....
 Worm   286 ------VERPNM----------------QGPRTKPRKPLQGSEV-LYAVGGWCSGDAIASIERLD 327

  Fly   327 PKK--MNWYELTAIPHIDQCNFGTAVLNNKLFIVGGAYDVFLKEYIHPFGFCYCPLRNTWMT-IA 388
            |.|  ..| :..|.....:|..|.|||.|.|:.||| :|.  :.|::... .|.|:.|.|.: :|
 Worm   328 PMKGGTTW-KCVAPMGKRRCGVGVAVLENLLYAVGG-HDG--QSYLNSIE-RYDPMTNQWSSDVA 387

  Fly   389 PIQQDRCRFSLN-AVGTQHLYAVGGILDDDNEEALRMISNVERYDIAKNVWTYMPSLQENRSQHA 452
            |..  .||.|:. |.....||||||   .|.|..|.:   ||:||..||.|..:.|:...|...:
 Worm   388 PTA--TCRTSVGVAAFNGSLYAVGG---QDGESCLDV---VEKYDPRKNEWAKVASMGTRRLGVS 444

  Fly   453 GVVVGDKLYISGGVHLANILASMWVFDTKTEVWQELASMPTPCCDHVLVAV-DNRIYACGGWHES 516
            ..||...:|..||.:....|.::..:|.:...|:|:..|.|. ..|:..|| |..|||.|| .::
 Worm   445 VSVVNGCIYAVGGSNGPAPLNTVERYDPRVGKWEEVRPMLTK-RKHLGTAVYDGYIYAVGG-RDT 507

  Fly   517 LTEWRVLVEHIYAYDIETNTWSVETKIPAPKFYTGVTAMGRTIFFVGGLDSTESIDRASAETMAY 581
            .||    :.....|.:|.:.|.....:...:...||..:|..::.|||.|....:  .|.|  .:
 Worm   508 TTE----LNTAERYSVERDEWQPVVAMSNRRSGVGVAVVGEKLYAVGGFDGQTYL--KSVE--IF 564

  Fly   582 DLDTKEW 588
            |.||..|
 Worm   565 DKDTNRW 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1812	NP_608397.1	BTB_POZ	33..151	CDD:453885	43/121 (36%)
		PHA03098	46..588	CDD:222983	160/577 (28%)
		KELCH repeat	344..390	CDD:276965	17/46 (37%)
		KELCH repeat	394..444	CDD:276965	20/50 (40%)
		KELCH repeat	448..492	CDD:276965	10/43 (23%)
		KELCH repeat	495..539	CDD:276965	14/44 (32%)
kel-20	NP_491322.2	PHA03098	56..572	CDD:222983	160/577 (28%)
		KELCH repeat	345..389	CDD:276965	17/47 (36%)
		KELCH repeat	393..437	CDD:276965	20/49 (41%)
		KELCH repeat	440..485	CDD:276965	11/44 (25%)
		KELCH repeat	487..531	CDD:276965	14/48 (29%)
		KELCH repeat	534..577	CDD:276965	13/42 (31%)