Protein Alignment CG1812 and LOC1281663

DIOPT Version :10

• Sequence 1: NP_608397.1
• Gene: CG1812 / 33049
• FlyBaseID: FBgn0031119
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: XP_061497908.1
• Gene: LOC1281663 / 1281663
• VectorBaseID: AGAMI1_004119
• Length: 675
• Species: Anopheles gambiae
• Alignment Length: 622
• Identity: 170/622 - (27%)
• Similarity: 274/622 - (44%)
• Gaps: 88/622 - (14%)

  Fly     2 AATPAPAVTPAATATSAAAKIPVNPVSPEE--------ETLLRGLNKLRNEEKLTDVTLI--VEE 56
            |:..|..||..:..:.|:..   :.||.:|        :.:|:.:......|||.||.||  |:.
Mosquito    15 ASVRASLVTDESHFSLASLN---SSVSQDEFFRCRDHSDVVLKRMQDYLQSEKLCDVVLIAGVDG 76

  Fly    57 HRFKAHRVVLAASSDYFCAMFADCAMIESRKDEINLYGIKARAMGSIIDYIYTSMLELNYDNIEE 121
            .|..|||:||:|||.||.|||.. .:.||:::||.|..:...|:.|:|.|.||..:|:..|.:|.
Mosquito    77 RRIPAHRLVLSASSAYFSAMFTG-QLRESQQEEITLQEVSGDALNSLIQYCYTGAIEIREDTVET 140

  Fly   122 ILAAATHVQVREVIDRCTIFLGAKIEMENCLAIAGMADIYGIMDLSERAYRYMCAHFEEFATTSD 186
            :||.|..:|:..::..|..||..::...|||..:..|:..|...|.:.|..|.|.||::.....:
Mosquito   141 LLATACLLQLSTIVGACCNFLARQLHPSNCLGFSLFAEQQGCTALLKLATAYTCQHFQQVWKNQE 205

  Fly   187 FKEMKVDQLRFILSS---NYPIDVAEQDLVR-LVCSFAIEQQLNESALGDLLRLIKWQHISYK-S 246
            |..:...||..:|.|   |.|   .||::.. |:.....:.:..:..:.:||.|||...:... .
Mosquito   206 FFMLDAAQLANLLRSDDLNVP---NEQEVFHALMAWIQYDAEGRKRHIPELLALIKLPLLQPSFI 267

  Fly   247 VDELRNMNCSLDKGKQLPLPTSYYNRIKQEHMGHLLNGVVSL--KDQSLPQGPTNMRGMELCLLK 309
            ||.:..:....::.:||         :.:....||:.|..||  ..::.|:..|..|     ||.
Mosquito   268 VDHVEALCGGANECQQL---------VMEAFKWHLIPGRRSLISTSRTRPRKSTMGR-----LLA 318

  Fly   310 IGGFEWNGLTNVIMCFSPKKMNWYELTAIPHIDQCNFGTAVLNNKLFIVGGAYDVFLKEYIHPFG 374
            :||.:.:.....|..:.|:...|..|..:| ..:..||.|||::||.||||...:.....:..|.
Mosquito   319 VGGMDGHKGAISIESYDPRLDKWTLLKNMP-TRRLQFGVAVLDDKLIIVGGRDGLKTLNTVDSFD 382

  Fly   375 FCYCPLRNT--WMTIAPIQQDRCRFSLNAVGT-QH----------LYAVGGILDDDNEEALRMIS 426
            .      ||  |.|:.|           .:|| :|          ||||||      .:....::
Mosquito   383 L------NTMCWSTLVP-----------PMGTPRHGLGVAFLEGPLYAVGG------HDGWSYLN 424

  Fly   427 NVERYDIAKNVWTYMPSLQENRSQHAGVVVGDKLYISGGVHLANILASMWVFDTKTEVWQELASM 491
            .|||:|.:...|:|:..:...||.....|:|.:||:.||...:....::..:|..|..|...|.|
Mosquito   425 TVERWDPSARTWSYVAPMSAMRSTAGVAVLGGRLYVIGGRDGSVCHRTVECYDPHTNKWTLRAPM 489

  Fly   492 --PTPCCDHVLVAVDNR-IYACGGWHESLTEWRVL--VEHIYAYDIETNTWSVETKIPAPKFYTG 551
              ...|   |.|.|.|. :||.|| |:.......:  .:.:..||..|:||::...:...:...|
Mosquito   490 NQRRGC---VGVGVLNGFLYALGG-HDCPPSNPAVCRTDTVERYDPTTDTWTLIASLSVGRDAIG 550

  Fly   552 VTAMGRTIFFVGGLDSTESIDRASAETMAYDLDTKEW 588
            |:.:|..:..:||.|..:.:....    .||.:|.||
Mosquito   551 VSVLGDWLVALGGYDGIQYLKIVE----QYDAETNEW 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1812	NP_608397.1	BTB_POZ	33..151	CDD:453885	44/119 (37%)
		PHA03098	46..588	CDD:222983	158/568 (28%)
		KELCH repeat	344..390	CDD:276965	16/47 (34%)
		KELCH repeat	394..444	CDD:276965	15/60 (25%)
		KELCH repeat	448..492	CDD:276965	13/45 (29%)
		KELCH repeat	495..539	CDD:276965	15/46 (33%)
LOC1281663	XP_061497908.1	None