Protein Alignment CG1812 and enc1

DIOPT Version :10

• Sequence 1: NP_608397.1
• Gene: CG1812 / 33049
• FlyBaseID: FBgn0031119
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: XP_002934870.1
• Gene: enc1 / 100271761
• XenbaseID: XB-GENE-966092
• Length: 589
• Species: Xenopus tropicalis
• Alignment Length: 639
• Identity: 154/639 - (24%)
• Similarity: 251/639 - (39%)
• Gaps: 121/639 - (18%)

  Fly    15 ATSAAAKIPVNPVSPEEETLLRGLNKLRNEEKLTDVTLIVEEHRFKAHRVVLAASSDYFCAMFAD 79
            |::.:..|.:...|...:::|..||.||.:...|||.|:.....|..||.||||.|.||.|||:.
 Frog    13 ASTGSMNIYLFHKSSYADSVLTHLNLLRKQCLFTDVLLLAGNRSFPCHRAVLAACSRYFEAMFSG 77

  Fly    80 CAMIESRKDEINLY-GIKARAMGSIIDYIYTSMLELNYDNIEEILAAATHVQVREVIDRCTIFLG 143
             .:.||:.:|:|.: .:....:..::||.|:|.:.:|.:|.|.:|.|...::.:::.|.|..||.
 Frog    78 -GLKESQANEVNFHSAVHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLE 141

  Fly   144 AKIEMENCLAIAGMADIYGIMDLSERAYRYMCAHFEEFATTSDFKEMKVDQLRFILSSNYPIDVA 208
            ..:...|||.:..::|.:....|.|.::|....:|:....|.||..:..|.:..:||:.   ::.
 Frog   142 KNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLNNFQTICKTEDFLLLPKDLVVQLLSNE---ELE 203

  Fly   209 EQDLVRLVCSFAIEQQLNESALGDLLRLIKWQHISYKSVDELRNMNCSLDKGKQLP----LPTSY 269
            .:|          |:.:.|||:       .|.|.      :|...:|.|.:..|..    ||..|
 Frog   204 TED----------ERMVYESAM-------NWIHY------DLNKRHCYLSELLQTVRLALLPAIY 245

  Fly   270 YNR--------IKQEHMGHLLNGVVSLKDQSLPQGPTNMRGM--ELC---------LLKIGGFEW 315
            ...        |||:....|:...:..|.:.|...     |:  .||         |..:||
 Frog   246 LMENVAMEELIIKQKKSKELVEEAIRCKLKILQND-----GVVTSLCAKPRKTGHALFLLGG--- 302

  Fly   316 NGLTNVIMCFSPKKMNWYELTAIPHID----QCNFGTAVLNNKLFIVGG-------AYDVFLKEY 369
                ...||.....::......||..|    :..|....:..|::|.||       :.||::.:.
 Frog   303 ----QTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDT 363

  Fly   370 IHPFGFCYCPLRNTWMTIAPIQQDRCRFSLNAVGTQH-LYAVG------GILDDDNEEALRMISN 427
            :|          ..|...||:..  .||...:...:| ||.||      |.|......:|:   .
 Frog   364 LH----------EEWSKAAPMLV--ARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLK---Q 413

  Fly   428 VERYDIAKNVWTYMPSLQENRSQHAGVVVGDKLYISGGVHLA-NILASMWVFDTKTEVWQELASM 491
            ||:||...|.||.:..|:|..|..|.|....||:..||..:: :.|..:..:|.....|...|:.
 Frog   414 VEQYDPVTNKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDPSENRWSVPATC 478

  Fly   492 PTPCCDHVLVAVDNRIYACGGWHESLTEWRVLVEHIYAYDIETNTWSVETKIPAPKFYTGVTAMG 556
            |.|........:..:|:..||    .||:...  ..|.::.||..|:....:.|.:......|.|
 Frog   479 PQPWRYTAAAVLGTQIFIMGG----DTEFSAC--SAYKFNSETYQWTKAGDVTAKRMSCHAVASG 537

  Fly   557 RTIFFVGGLDSTESIDRASAETMAYDLDTKEWWHEKDSWDSPNDVWESTCVAIY 610
            ..:|.|||....:     ..:|:             |.:|...|||.|.....|
 Frog   538 NKLFVVGGYFGIQ-----RCKTL-------------DCYDPTLDVWNSITTVPY 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1812	NP_608397.1	BTB_POZ	33..151	CDD:453885	39/118 (33%)
		PHA03098	46..588	CDD:222983	139/584 (24%)
		KELCH repeat	344..390	CDD:276965	10/52 (19%)
		KELCH repeat	394..444	CDD:276965	17/56 (30%)
		KELCH repeat	448..492	CDD:276965	11/44 (25%)
		KELCH repeat	495..539	CDD:276965	9/43 (21%)
enc1	XP_002934870.1	BTB_POZ_KLHL37_ENC1	6..152	CDD:349576	45/139 (32%)
		PHA03098	60..566	CDD:222983	138/583 (24%)
		BACK_KLHL37_ENC1	145..242	CDD:350590	25/122 (20%)
		KELCH repeat	330..374	CDD:276965	10/53 (19%)
		KELCH repeat	378..431	CDD:276965	17/55 (31%)
		KELCH repeat	434..480	CDD:276965	11/45 (24%)
		KELCH repeat	528..573	CDD:276965	13/62 (21%)