Protein Alignment CG1812 and kbtbd3

DIOPT Version :10

• Sequence 1: NP_608397.1
• Gene: CG1812 / 33049
• FlyBaseID: FBgn0031119
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: XP_073780249.1
• Gene: kbtbd3 / 100003277
• ZFINID: ZDB-GENE-131016-5
• Length: 615
• Species: Danio rerio
• Alignment Length: 628
• Identity: 145/628 - (23%)
• Similarity: 239/628 - (38%)
• Gaps: 138/628 - (21%)

  Fly    27 VSPEEETLLR----------GLNKLRNEEKLTDVTLIVEEHRFKAHRVVLAASSDYFCAMFADCA 81
            |||:....||          .|...|..:.|.|.::.|::.....||.||||.|.:|.||| :..
Zfish    23 VSPQRCVFLRCECVGQQIISVLQGFRQRKLLLDFSIHVQDETLLCHRCVLAACSHFFRAMF-ELD 86

  Fly    82 MIESRKDEINLYGIKARAMGSIIDYIYTSMLELNYDNIEEILAAATHVQVREVIDRCTIFLGAKI 146
            |.|.....:.|..:.|:|:.:.:|:.|:..:|:..||:|.:...|:.:||..::..|:.||...:
Zfish    87 MRECVDGSVTLSNLSAQAVHTFLDFAYSGEIEVREDNVEMLFQMASFLQVDFLLRSCSDFLLESL 151

  Fly   147 EMENCLAIAGMADIYGIMDLSERAYRYMCAHFEEFATTSDFKEMKVDQL-RFILSSNYPIDVAEQ 210
            ::.|||.:..:|:.||...|...|..::..:|:..:.:.:|.|:....| |.:||....:...|.
Zfish   152 DVSNCLHLLELAEGYGSTQLLRGAIDFITQNFQTVSCSVEFLELPSPVLERVLLSDELRVPDEET 216

  Fly   211 DLVRLVCSFAIEQQLNESALGDLLRLIKWQHISYKSV----------DELRNM-NCSLDKGKQLP 264
            .|..|:|....:.....|.:..||..::..||...::          ||.||| ..:|.:.:|..
Zfish   217 VLQALLCWVKHDPSTRTSLMQQLLACVRLHHIPIATLENAAQSDMLTDECRNMLTHALAQTQQFS 281

  Fly   265 --------LPTSYYNRI--KQEHMGH-LLNGVVSLKDQSLPQGPTNMRGMELCLLKIGGFEWNGL 318
                    ..||.|..:  .:|.|.| ....:||.:...||:..  ||     :|::.|
Zfish   282 GLFTDARVSTTSTYIFVHKTEESMRHTFCYEIVSDRWTPLPEDA--MR-----ILELPG------ 333

  Fly   319 TNVIMCFSPKKMNWYELTAIPHIDQCNFGTAVLNNKLFIVGG-------------------AYDV 364
             :|:..|:                          .||||.||                   |.|.
Zfish   334 -SVMTSFA--------------------------EKLFISGGCHSDCPRSIRTHISSPHHEATDE 371

  Fly   365 FLKEYIHPFGFCYCPLRNTWMTIAPIQQDRCRFSLNAVGTQHLYAVGGILDDDNEEALRMISNVE 429
            |         :||||:.::: |.||..:.........|..|.||.:||  ...:...:..|.:|:
Zfish   372 F---------WCYCPIAHSF-TPAPRMRHTRTMHTCVVALQRLYVIGG--KPRSSRNVPSIVDVD 424

  Fly   430 RYDIAKNVWTYMPSLQENRSQHAGVVVGDKLYISGG-VHLAN----ILASMWVFDTKTEVWQEL- 488
            .||.....|..:..|.:........|.|:.:|..|. |..::    :|...:.:|...:.|..|
Zfish   425 YYDPLMREWISVSPLPKGIYFPEASVCGNVIYALGSEVEFSDAFNPLLDCFFRYDAVADQWSHLV 489

  Fly   489 --------ASMPTPCCDHVLVAVDNRIYACGGWHESLTEWRVLVEHIYAYDIETNTWSVETKIPA 545
                    |.:....|      |:..:|.|     .|:.::|     |::..:...|..|.....
Zfish   490 AEFGQFFHARLVKSVC------VNETLYLC-----DLSTYKV-----YSFCADEGVWKGEGSFEC 538

  Fly   546 PKFYTGVTAMGRTIFFVGGLDSTESIDRASAETMAYDLDTKEW 588
            ..|......:...||.:||   ..|.|..|.|...||....||
Zfish   539 AGFNAAAVGVRGKIFILGG---DYSPDEISDEVQVYDSSRSEW 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1812	NP_608397.1	BTB_POZ	33..151	CDD:453885	35/127 (28%)
		PHA03098	46..588	CDD:222983	136/597 (23%)
		KELCH repeat	344..390	CDD:276965	15/64 (23%)
		KELCH repeat	394..444	CDD:276965	11/49 (22%)
		KELCH repeat	448..492	CDD:276965	10/57 (18%)
		KELCH repeat	495..539	CDD:276965	8/43 (19%)
kbtbd3	XP_073780249.1	None