Protein Alignment RhoGAP19D and Chn1

DIOPT Version :10

• Sequence 1: NP_001285496.1
• Gene: RhoGAP19D / 33048
• FlyBaseID: FBgn0031118
• Length: 2206
• Species: Drosophila melanogaster
• Sequence 2: XP_006234448.1
• Gene: Chn1 / 84030
• RGDID: 620139
• Length: 476
• Species: Rattus norvegicus
• Alignment Length: 305
• Identity: 84/305 - (27%)
• Similarity: 146/305 - (47%)
• Gaps: 40/305 - (13%)

  Fly  1136 DASGSHHVSALPAAAAIVAATSDSISPVMKARKSSSHKHIPDKDLGSPKSKNWKDLL--FRRGGS 1198
            :|:|...||.....:.:..||......:.|..|..:.|      :.:.:..:|.:..  |..|..
  Rat   189 EATGQDGVSEKRLTSLVRRATLKENEQIPKYEKVHNFK------VHTFRGPHWCEYCANFMWGLI 247

  Fly  1199 GSG------GVSHHDLAS---PSACA--AKQIGSIGVPLRSCPMSK-VNAYV---PHLVEVCTNI 1248
            ..|      |::.|...|   |:.|.  .|.:..:    .||.::. |.|::   |.:|::|...
  Rat   248 AQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKV----YSCDLTTLVKAHITKRPMVVDMCIRE 308

  Fly  1249 VETKGLGVVGIYRIPGNKAAISELSELVNTKDFQFE-----SCASDDRWEDVNVVSSLLKLFIRS 1308
            :|::||...|:||:.|       .|:|:......|:     :..|.:.:||:|:::..|||:.|.
  Rat   309 IESRGLNSEGLYRVSG-------FSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRD 366

  Fly  1309 LPDALMPASYYINFIEADKKFGL-ERIVLLREIVESLPRHPYETMKHLIRHLCRVSGNCDVNRME 1372
            ||..|:....|..|||:.|.... |::..|.|.:.|||....||:::|:.||.||:.:...|.|.
  Rat   367 LPIPLITYDAYPKFIESAKIVDPDEQLETLHEALRSLPPAHCETLRYLMAHLKRVTLHEKENLMS 431

  Fly  1373 PKNLAIIFGPSIIRTPNDTLETAVKDMKHQCRIVELLVTQYDYFF 1417
            .:||.|:|||:::|:|......|:.|:::|..:||||:...|..|
  Rat   432 AENLGIVFGPTLMRSPELDPMAALNDIRYQRLVVELLIKNEDILF 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP19D	NP_001285496.1	PDZ_canonical	52..204	CDD:483948
		RhoGAP_ARHGAP21	1221..1417	CDD:239860	64/205 (31%)
Chn1	XP_006234448.1	SH2_a2chimerin_b2chimerin	59..145	CDD:198215
		C1_alphaCHN	218..274	CDD:410406	12/61 (20%)
		RhoGAP_chimaerin	283..476	CDD:239837	64/199 (32%)