Protein Alignment RhoGAP19D and arhgap15

DIOPT Version :9

• Sequence 1: NP_001285496.1
• Gene: RhoGAP19D / 33048
• FlyBaseID: FBgn0031118
• Length: 2206
• Species: Drosophila melanogaster
• Sequence 2: NP_001122027.1
• Gene: arhgap15 / 100003547
• ZFINID: ZDB-GENE-070912-314
• Length: 465
• Species: Danio rerio
• Alignment Length: 598
• Identity: 127/598 - (21%)
• Similarity: 233/598 - (38%)
• Gaps: 173/598 - (28%)

  Fly   838 PISIPIPVAAVVEPQKTKSLVEEHPDPTYDVIGGTGGGHEFIETPNGLEDVRLSAHGSRRASMSS 902
            |.::.:|.|..:..:.::|...|....|..::....   |.::.|       ::.|...::..:|
Zfish     4 PPALVLPGAVQLRIKNSQSSTGERLSQTKSMVLPEA---ETLQKP-------INRHRRNQSQHNS 58

  Fly   903 DMRSSIHIDAELNGKYVPNELEAFETEIEIKSSCINGKRMSEYRSWRQVKLEIKGDLLRIYSGRH 967
            ::  |:.:...|.|:|: |:.:..|          .||::.  ::|....:.:..:.|..|....
Zfish    59 EV--SVGLQPVLKGEYL-NKAKIAE----------GGKKLR--KNWTLTWVVLSSNQLLFYKESK 108

  Fly   968 AKSEHNV--------IELDIRNFKFFDESMDKK-----------KYLIRMQSKPSPSGAHLASLG 1013
            .::..|:        ::|:....::..|...:|           ::|::....|:.|..|.|
Zfish   109 QEAVSNLKPGGKPDGVDLNGAVIEWTTEKSSRKNVIQITTPTGHEFLLQADHFPTISKWHDA--- 170

  Fly  1014 NELNLDEGHDKLLTSSGSSSANEPAANAASALTASTSSSTC-SSGPYTEILFKTKSSNEMKRLFG 1077
                :.:..|.|.:.||..|....|.:.::: |...|..|| ||.|..:   :|||.:....:|
Zfish   171 ----IKKAVDILSSGSGGQSCGRAALHRSNS-TECLSRPTCESSKPKPK---ETKSEHRRSIMF- 226

  Fly  1078 LLQWKDSLNYDDNEHQPQGKQLAEPQKTVASASYLDDVQGGASAADSSPLSSHSGGIADASGSHH 1142
                  .|||                                ||:||          ||.:|
Zfish   227 ------KLNY--------------------------------SASDS----------ADKNG--- 240

  Fly  1143 VSALPAAAAIVAATSDSISPVMKARKSSSHKHIPDKDLGSPKSKNWKDLLFRRGGSGSGGVSHHD 1207
                                 :|.|                    .|..:.||
Zfish   241 ---------------------VKNR--------------------LKKFISRR------------ 252

  Fly  1208 LASPSACAAKQIGSIGVPLRSCPM----SKVNAYVPHLVEVCTNIVETKGLGVVGIYRIPGNKAA 1268
               ||....::.|.|...:..|.|    .:....||..|::|...||.:||...||||:.||.|.
Zfish   253 ---PSMKTLQEKGIIKDRVFGCHMLTLCDREKTTVPKFVKLCVEEVEKRGLEADGIYRVSGNLAI 314

  Fly  1269 ISELSELVNTKDFQFESCASDDRWEDVNVVSSLLKLFIRSLPDALMPASYYINFIEADK-KFGLE 1332
            |.:|..||:.::   |....|.:|||::|::..||:|.|.||:.|.|..::..|:|..| |...:
Zfish   315 IQKLRFLVDQEE---ELDLGDSQWEDIHVITGALKMFFRELPEPLFPFRFFDLFVETIKIKEPTQ 376

  Fly  1333 RIVLLREIVESLPRHPYETMKHLIRHLCRVSGNCDVNRMEPKNLAIIFGPSIIRTPNDTLETAVK 1397
            ::..:::::..||:..:.|||.|..||.||......|.|..:.::|:|||:::....::....|
Zfish   377 KVQAMKKLIHQLPKPNHNTMKLLFHHLRRVLTKSQKNLMSTQGVSIVFGPTLMWPEFESGNMEV- 440

  Fly  1398 DMKHQCRIVELLV 1410
            :|.:|.:|||.::
Zfish   441 NMVYQNQIVECIL 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP19D	NP_001285496.1	PDZ_signaling	<151..205	CDD:238492
		RhoGAP_ARHGAP21	1221..1417	CDD:239860	62/195 (32%)
arhgap15	NP_001122027.1	PH	67..175	CDD:278594	19/127 (15%)
		PH_ARHGAP9-like	68..176	CDD:270053	19/127 (15%)
		RhoGAP_ARHGAP27_15_12_9	269..453	CDD:239868	61/187 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23176
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010