DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT3 and Sgsm2

DIOPT Version :9

Sequence 1:	NP_001162808.1	Gene:	GstT3 / 33047	FlyBaseID:	FBgn0031117	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001361617.1	Gene:	Sgsm2 / 97761	MGIID:	2144695	Length:	1050	Species:	Mus musculus

Alignment Length:	245	Identity:	54/245 - (22%)
Similarity:	83/245 - (33%)	Gaps:	85/245 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LKRRVPSRQPTNLRMSAPIRYYYDLMSQPSRALFIIFRLSNM---PFEDCVVA------------ 76
            :::|..|...:..|::|..|.|.:.:.|.||.. :::..:|:   |.||....
Mouse   225 IRKRHSSGSASEDRLAACAREYVESLHQNSRTR-LLYGKNNVLVQPKEDMEAVPGYLSLHQSAEN 288

  Fly    77 ---------LRNGEHLTEDFKKEIN-------RFQRVPCIHDNGYKLAESVAILRYLSAKG--KI 123
                     |.||.....:.:|.:.       .|.::.|||.:..|   |...|..:|..|  :.
Mouse   289 LTLKWTPNQLMNGTLGDSELEKSVYWDYALVVPFSQIVCIHCHQQK---SGGTLVLVSQDGIQRP 350

  Fly   124 PEHLYPKYFVDQSRVDEFLEWQHMSLRLTCAMYFRTVWLEPLLTGRTPSEAKIETFRMQMERNLD 188
            |.|              |.:..|:...|:|           |..|..|        |.|:|..|
Mouse   351 PLH--------------FPQGGHLLSFLSC-----------LENGLLP--------RGQLEPPL- 381

  Fly   189 VVEEVWLE---GKDF---LTGSSLTVADIFAACEIEQTRMADYDVRIKYP 232
                 |.:   ||.|   ...||:...|:.   |:...|..||..||.||
Mouse   382 -----WTQQGKGKVFPKLRKRSSIRSIDVE---ELGVGRATDYVFRIIYP 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT3	NP_001162808.1	GST_N_Theta	45..121	CDD:239348	21/106 (20%)
		GstA	47..243	CDD:223698	49/225 (22%)
		GST_C_Theta	135..259	CDD:198292	26/104 (25%)
Sgsm2	NP_001361617.1	RUN	42..185	CDD:367169
		PH_RUTBC	256..424	CDD:275431	45/214 (21%)
		TBC	<838..1006	CDD:214540
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900