DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT3 and Tbc1d8

DIOPT Version :9

Sequence 1:	NP_001162808.1	Gene:	GstT3 / 33047	FlyBaseID:	FBgn0031117	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_006244913.1	Gene:	Tbc1d8 / 680133	RGDID:	1595491	Length:	1150	Species:	Rattus norvegicus

Alignment Length:	182	Identity:	33/182 - (18%)
Similarity:	67/182 - (36%)	Gaps:	50/182 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 ALFIIFRLSNMPFEDCVVALRNGEHLTEDFKKEINRFQRVPCIHDNGYKLAESVAILRYLSA--- 119
            |.|:..::..:..|:....|...|...|.|::.:.:|:.       .:...|:..::.|.|.
  Rat   126 ASFVKGKVKALIAEETSSRLAEQEEEPEKFREALVKFEA-------RFNFPEAEKLVTYYSCCCW 183

  Fly   120 KGKIPEHLYPKYFVDQSRVDEFLEWQHMSLRLTCAMYF------RTV--WLEPLLTGRTPSEAKI 176
            ||::|..                .|.::|:...|...|      :.|  |::.....||.:....
  Rat   184 KGRVPRQ----------------GWLYLSINHLCFYSFFLGKELKLVIPWVDIQKLERTSNVFLT 232

  Fly   177 ETFRMQMERNLDVVEEVWLEGKDFLTGSSLTVADIFAACEIEQTRMADYDVR 228
            :|.|:..:.          :.:||.|  .|.:.::|...|    ::||..:|
  Rat   233 DTIRITTQN----------KERDFST--FLNLDEVFKIME----QLADVTLR 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT3	NP_001162808.1	GST_N_Theta	45..121	CDD:239348	11/65 (17%)
		GstA	47..243	CDD:223698	33/182 (18%)
		GST_C_Theta	135..259	CDD:198292	19/102 (19%)
Tbc1d8	XP_006244913.1	PH-GRAM1_TBC1D8	171..269	CDD:270156	24/130 (18%)
		PH-GRAM2_TBC1D8	311..406	CDD:270160
		TBC	520..726	CDD:214540
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900