DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT3 and tbc1d2

DIOPT Version :9

Sequence 1:	NP_001162808.1	Gene:	GstT3 / 33047	FlyBaseID:	FBgn0031117	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_689604.6	Gene:	tbc1d2 / 561110	ZFINID:	ZDB-GENE-140106-100	Length:	926	Species:	Danio rerio

Alignment Length:	207	Identity:	40/207 - (19%)
Similarity:	70/207 - (33%)	Gaps:	85/207 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 LRNGEHLTEDFKKEINRF----------QRVPCIHDNGYKLAESVAILRYLSAKGKIPEHLYPKY 131
            ||.|  |..:::..:.||          :|.|   |..::|.|          |.:...||.|:
Zfish   620 LRTG--LPHEYRVRVWRFMIQTRTKSLRERHP---DRYHELCE----------KSRSSPHLVPR- 668

  Fly   132 FVDQSRVDEFLEWQHMSLRLTCAMYFRTVWLEPLLTGRTPSEAKIETFRMQMERNLDVVEEVW-- 194
               |.::|       :...||...:|           ..|:...|:    ::||.|....  |
Zfish   669 ---QIQLD-------LDRTLTSNKHF-----------SPPTSPLIQ----KLERVLQAFS--WHN 706

  Fly   195 -----LEGKDFLTGSSLTV----ADIF--------------------AACEIEQTRMADYDVRIK 230
                 ::|.:.|...:|.|    ||.|                    ..|:.:|..:.|..:. |
Zfish   707 PTIGYVQGLNRLAAIALLVLQEEADAFWCLVVIVEHIMPPNYFTKDLVGCQADQRVLKDLMLE-K 770

  Fly   231 YPKIRAWLKRVR 242
            .|::.|.|:.::
Zfish   771 LPRLTAHLEALK 782

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT3	NP_001162808.1	GST_N_Theta	45..121	CDD:239348	11/53 (21%)
		GstA	47..243	CDD:223698	40/207 (19%)
		GST_C_Theta	135..259	CDD:198292	25/139 (18%)
tbc1d2	XP_689604.6	PH	56..146	CDD:278594
		PH_TBC1D2A	57..153	CDD:269966
		TBC	621..837	CDD:214540	39/206 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900