DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT3 and tbc1d15

DIOPT Version :9

Sequence 1:	NP_001162808.1	Gene:	GstT3 / 33047	FlyBaseID:	FBgn0031117	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_005159143.1	Gene:	tbc1d15 / 492676	ZFINID:	ZDB-GENE-041111-251	Length:	665	Species:	Danio rerio

Alignment Length:	229	Identity:	51/229 - (22%)
Similarity:	87/229 - (37%)	Gaps:	74/229 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VSFLASLLGLSNDEDQLQVAFDEVLKRRVPSRQPTNLRMSAPIRYYYDLMSQPSRALFIIFRLSN 67
            |||:..:  ..|.|:|:|....:::       |.:.|.....:.::..|.:|.|..|:..||
Zfish   457 VSFMDEM--HENFEEQMQGMKTQLI-------QLSTLLRLLDLAFWNYLEAQDSGYLYFCFR--- 509

  Fly    68 MPFEDCVVALRNGEHLTEDFKKEINRFQ-----------RVPCIHDNGYKLAESVAILRYLSAKG 121
                          .|...||:|:: ||           |:||   ..:.|....|||.  |.|.
Zfish   510 --------------WLLIRFKRELH-FQDVLRLWEVMWTRLPC---QNFHLLVCCAILD--SEKQ 554

  Fly   122 KIPEHLYPKYFVDQSRVDEFLEW-QHMSLRLTCAMYFRTVWLEPLLTGRTPSEAKIETFRMQMER 185
            ||.:..|        ..:|.|:. ..:|::|.         :|.:|       :|.|:..||::.
Zfish   555 KIMDRKY--------GFNEILKHINELSMKLD---------IEEIL-------SKSESICMQIKS 595

  Fly   186 NLDVVEEVWLEGKDFLTGSSLTVADIFAACEIEQ 219
            ..|:...|     ..:.|.: ||::..||.|..:
Zfish   596 CKDLPHSV-----SEILGLN-TVSEPSAALETSE 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT3	NP_001162808.1	GST_N_Theta	45..121	CDD:239348	20/86 (23%)
		GstA	47..243	CDD:223698	42/185 (23%)
		GST_C_Theta	135..259	CDD:198292	18/86 (21%)
tbc1d15	XP_005159143.1	DUF3548	4..220	CDD:192931
tbc1d15	XP_005159143.1	TBC	322..557	CDD:214540	31/131 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900