DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT3 and Tbc1d2

DIOPT Version :9

Sequence 1:	NP_001162808.1	Gene:	GstT3 / 33047	FlyBaseID:	FBgn0031117	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_006538109.1	Gene:	Tbc1d2 / 381605	MGIID:	2652885	Length:	923	Species:	Mus musculus

Alignment Length:	305	Identity:	59/305 - (19%)
Similarity:	108/305 - (35%)	Gaps:	85/305 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ASLLGLSNDEDQLQVAFDEV-----LKRRVPSRQPTNLRMS--APIR---------YYYDLMSQP 55
            ::.|..:.|.|:|::...:|     |.:||.:.:....|::  |.:|         :...||.:.
Mouse   351 SAYLAATEDRDRLELVRHKVRQIAELNQRVEALEQGRERLAHEAGLREQQVQALQQHVQLLMDKN 415

  Fly    56 SRALFIIFRLSNMPFEDCV--VALRNG---------EHLTEDFK--KEINRF--QRVPCIHDNGY 105
            .....:|.:|:....||..  ....||         |||.:|.:  :..|||  ..:..:.....
Mouse   416 HAKQQVICKLTQKLTEDLAQPADATNGDFLSQQERMEHLKDDMEAYRTQNRFLNSEIHQVTKIWR 480

  Fly   106 KLAESVAIL----RYLSAK-----------------------GKIPEHLYPKYFVDQSRVDEFLE 143
            |:||....|    .||.|:                       |..||.|       |..:.|.|:
Mouse   481 KVAEKEKALLTKCAYLQARNCQVESKYLAGLRRLQEAAGAEAGDFPELL-------QQLIQEALQ 538

  Fly   144 WQHMSLRLTCAMYFRTVWLEPLLTGRTPSEAKIETFRMQMERNLDVVEEVWLEGKDFLTGSSL-- 206
            |:        |....:|.|.|:..........:..:.|:..:.|..::.:.:.....|...::
Mouse   539 WE--------AGEADSVGLSPVSEYDDYGFLTVPDYEMEDLKLLAKIQALEVRSHHLLAHEAVER 595

  Fly   207 -------TVADIFAACEIEQTRMADYDVRIKYPKIRAWL--KRVR 242
                   |:.::..:.|::|...|... |...|::..||  :|||
Mouse   596 PLRDRWATLTELTPSAELKQLLRAGVP-REHRPRVWRWLVHRRVR 639

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT3	NP_001162808.1	GST_N_Theta	45..121	CDD:239348	23/126 (18%)
		GstA	47..243	CDD:223698	48/249 (19%)
		GST_C_Theta	135..259	CDD:198292	22/119 (18%)
Tbc1d2	XP_006538109.1	PH_TBC1D2A	45..146	CDD:269966
		PRK14951	<192..404	CDD:237865	11/52 (21%)
		COG4913	<300..>565	CDD:227250	45/228 (20%)
		TBC	620..832	CDD:214540	7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900