DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT3 and Tbc1d2

DIOPT Version :9

Sequence 1:	NP_001162808.1	Gene:	GstT3 / 33047	FlyBaseID:	FBgn0031117	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_006238118.1	Gene:	Tbc1d2 / 313234	RGDID:	1306860	Length:	924	Species:	Rattus norvegicus

Alignment Length:	324	Identity:	65/324 - (20%)
Similarity:	107/324 - (33%)	Gaps:	120/324 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ASLLGLSNDEDQLQVAFDEV-----LKRRVPSRQPTNLRM--SAPIR---------YYYDLMSQP 55
            ::.|..:.|.|:|::...:|     |.:||.:.:....|:  .|.:|         :...||.:.
  Rat   349 SAYLAATEDRDRLELVRHKVRQIAELNQRVEALEQDRERLVHEAGLREQQVQALQQHVQLLMDKN 413

  Fly    56 SRALFIIFRLSNMPFEDCV----VALRNG---------EHLTEDFK--KEINRF--QRVPCIHDN 103
            .....:|.:||....||..    ....||         |||.:|.:  :..|||  ..:..:...
  Rat   414 QAKQQVICKLSQKLTEDLAQPQPADATNGDFLSQQERLEHLKDDMEAYRTQNRFLNSEIHQVTKI 478

  Fly   104 GYKLAESVAIL----RYLSAK-----------------------GKIPEHLYPKYFVDQSRVDEF 141
            ..|:||....|    .||.|:                       |..||.|       |..|.|.
  Rat   479 WRKVAEKEKALLTKCAYLQARNCQVESKYLAGLRRLQEAAGAEPGDFPELL-------QQLVQEA 536

  Fly   142 LEWQHMSLRLTCAMYFRTVWLEPLLTGRTPSE--------------------AKIETFRMQMER- 185
            |:|:       ......:|.|.|:      ||                    |||:...::...
  Rat   537 LQWE-------AGEASDSVGLSPV------SEYDDYGFLTVPDYEVEDLKLLAKIQALEVRSHHL 588

  Fly   186 -NLDVVE----EVWLEGKDFLTGSSLTVADIFAACEIEQTRMADYDVRIKYPKIRAWL--KRVR 242
             .|:.||    :.|           .|:.::..:.|::|...|... |...|::..||  :||:
  Rat   589 LALEAVERPLRDRW-----------ATLTELMPSAELKQLLRAGVP-REHRPRVWRWLVHRRVQ 640

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT3	NP_001162808.1	GST_N_Theta	45..121	CDD:239348	24/128 (19%)
		GstA	47..243	CDD:223698	54/268 (20%)
		GST_C_Theta	135..259	CDD:198292	27/136 (20%)
Tbc1d2	XP_006238118.1	PH_TBC1D2A	44..145	CDD:269966
		PH	44..137	CDD:278594
		TBC	621..833	CDD:214540	6/21 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900