DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT3 and Tbc1d8b

DIOPT Version :9

Sequence 1:	NP_001162808.1	Gene:	GstT3 / 33047	FlyBaseID:	FBgn0031117	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001074968.1	Gene:	Tbc1d8b / 245638	MGIID:	1918101	Length:	1114	Species:	Mus musculus

Alignment Length:	235	Identity:	46/235 - (19%)
Similarity:	82/235 - (34%)	Gaps:	81/235 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LASLLGLSNDED---QLQVAFDEVLKRRVPSRQPTNLRMSAPI---------------------R 46
            |..||...:|.:   .|...||.|:.:..|  .|:|::..:.|                     :
Mouse   689 LDKLLTCKDDAEAVTALNRFFDNVINKDSP--LPSNVQQGSNISNEKSDHTKVDITDLIKESNEK 751

  Fly    47 Y----YYDLMSQPSR-ALFIIFRLS--------NMPFEDCVVALRNGEHLTEDFKKEINRFQRVP 98
            |    |.|:.|...| .|::|..|.        .:..:|..::|:..:.|...||||:
Mouse   752 YGSIRYEDIHSMRCRNRLYVIQTLEETTKQNVLRVVSQDVKMSLQELDELYVIFKKEL------- 809

  Fly    99 CIHDNGYKLAESVAILRYLSAKGKIPEHLYPKY-FVDQSRVDEFLEWQHMSLRLTCAMYFRTVW- 161
                       .::...|||..|.  :|..|.. :::|.::|              ...||.::
Mouse   810 -----------FISCYWYLSCPGL--KHHDPSLPYLEQYQID--------------CQQFRVLYH 847

  Fly   162 -LEPLLTGRTPSEAKIETFRMQMERNLDVVEEVWLEGKDF 200
             |.|...........:.|||: ::.|.|.:    :..|:|
Mouse   848 LLSPWAHSANRDSLALWTFRL-LDENSDCL----INFKEF 882

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT3	NP_001162808.1	GST_N_Theta	45..121	CDD:239348	19/109 (17%)
		GstA	47..243	CDD:223698	34/170 (20%)
		GST_C_Theta	135..259	CDD:198292	13/68 (19%)
Tbc1d8b	NP_001074968.1	PH-GRAM1_TBC1D8B	156..254	CDD:275419
		PH-GRAM2_TBC1D8B	296..388	CDD:270159
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	399..420
		TBC	485..693	CDD:214540	1/3 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	938..957
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1032..1061
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900